The salivary glands of mutant embryos are wider and shorter than normal, appearing to have bulges and bubbles in their lumens. Malpighian tubules are abnormal. Homozygous embryos have both sensory and nonsensory cuticular hairs which resemble those of wild-type embryos.

Homozygous embryos do not complete head involution. The salivary glands are enlarged, with lumens distended by bulges and bubbles. Malpighian tubules are abnormal, remaining coiled near their juncture with the hindgut rather than extending anteriorly as in the wild-type. Abnormal branching of the tubules, consisting of short dead-ends extending only the length of one or two cells, is seen. The diameter of the Malpighian tubules is similar to wild-type. The hindgut appears normal and the midgut constrictions appear slightly less pronounced than wild-type. Abnormalities in the peripheral nervous system cannot be detected.

Mutant phenotype can be rescued to adulthood by P-element mediated introduction of a genomic fragment spanning the entire transcription unit. Rescue by zip cDNA driven from a minimal Hsp70 promoter allows rescue to larvae and intermittant heat shocks allows some rescue to adulthood. During the late dorsal closure stages myosin is absent from the leading edge causing a prominent, irregularly shaped dorsal opening in the cuticle.

rib¹, zip^mhc-c1.3 has viable phenotype

rib², zip^mhc-c1.3 has viable phenotype

Df(2R)P34, zip^mhc-c1.3 has viable phenotype

zip^mhc-c1.3 is a suppressor of embryonic/larval salivary gland | embryonic stage phenotype of raw¹

zip^mhc-c1.3 is a suppressor of Malpighian tubule phenotype of raw¹

zip^mhc-c1.3 is a suppressor of embryonic/larval salivary gland | embryonic stage phenotype of rib¹

zip^mhc-c1.3 is a suppressor of Malpighian tubule phenotype of rib¹