FlyBase Allele Report: Dmel\Sry-β::Sry-δ[DB56]

General Information

Symbol

Dmel\Sry-β::Sry-δ^DB56

Species

D. melanogaster

Name

FlyBase ID

FBal0039043

Feature type

allele

Associated gene

Sry-β::Sry-δ

Associated Insertion(s)

Carried in Construct

P{sryDB56,ry⁺}

Also Known As

P{ry⁺,sryDB56}

Key Links

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(Payre et al., 1994)

Progenitor genotype

Carried in construct

P{sryDB56,ry⁺}

Cytology

Description

Construct: Zinc fingers 5 and 6 of Sry-δ has been replaced by the equivalent region from Sry-β, expression is driven by the Sry-δ promoter. This finger swap results in 36 of 58 amino acid changes of which 7 are conservative.

(Payre et al., 1994)

Allele components

Component

Use(s)

Encoded product / tool

Sry-β::Sry-δ

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

female sterile

(Payre et al., 1994)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Suppressor of

Statement

Reference

Sry-β::Sry-δ^DB56, Sry-δ¹⁴, Df(3R)X3F is a non-suppressor of visible | homeotic phenotype of mira^{Δ103.αTub67C.mGFP6}

(Irion et al., 2006)

Phenotype Manifest In

NOT Suppressor of

Statement

Reference

Sry-β::Sry-δ^DB56, Sry-δ¹⁴, Df(3R)X3F is a non-suppressor of embryonic abdomen | ectopic phenotype of mira^{Δ103.αTub67C.mGFP6}

(Irion et al., 2006)

Sry-β::Sry-δ^DB56, Sry-δ¹⁴, Df(3R)X3F is a non-suppressor of embryonic head phenotype of mira^{Δ103.αTub67C.mGFP6}

(Irion et al., 2006)

Sry-β::Sry-δ^DB56, Sry-δ¹⁴, Df(3R)X3F is a non-suppressor of embryonic thorax phenotype of mira^{Δ103.αTub67C.mGFP6}

(Irion et al., 2006)

Sry-β::Sry-δ^DB56, Sry-δ¹⁴, Df(3R)X3F is a non-suppressor of primordial germ cell | ectopic phenotype of mira^{Δ103.αTub67C.mGFP6}

(Irion et al., 2006)

Additional Comments

Genetic Interactions

Statement

Reference

Embryos that express mira^{Δ103.αTub67C.T:Avic\GFP-m6} and Sry-β::Sry-δ^DB56 in a Sry-δ¹⁴/Df(3R)X3F background show that same phenotype as embryos that express mira^{Δ103.αTub67C.T:Avic\GFP-m6} in a wild-type background.

(Irion et al., 2006)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

Introduction of the construct P{sryDB56,ry⁺} causes almost complete rescue of the lethality of Sry-δ^- hemizygotes, males are fertile but females cannot give viable progeny although egg laying and ovary morphology are normal.

(Payre et al., 1994)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Sry-β::Sry-δ^DB56

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections

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