FB2026_03 , released September 17, 2026
Allele: Ecol\lacZab-94
Open Close
General Information
Symbol
Ecol\lacZab-94
Species
E. coli
Name
FlyBase ID
FBal0040626
Feature type
allele
Associated gene
Ecol\lacZ
Associated Insertion(s)
P{lwB}ab94
Carried in Construct
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Tepass and Knust, 1993)
Progenitor genotype
Associated Insertion(s)
P{lwB}ab94
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{lwB}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      embryonic stage
      stomatogastric nervous system
      (Hu et al., 1995)
      embryonic stage 9 -- 13
      VUM precursor
      (Hu et al., 1995)
      ventral midline of embryo | precursor
      (Hu et al., 1995)
      embryonic stage 10
      esophagus primordium | uniform
      (Hartenstein et al., 1994)
      labral segment

      Comment: homogeneously distributed

      (Hartenstein et al., 1994)
      embryonic stage 10 -- 11
      precursor cell of the stomatogastric nervous system | presumptive
      (Hartenstein et al., 1994)
      embryonic stage 10 -- 15
      precursor cell of the stomatogastric nervous system
      (Hartenstein et al., 1994)
      embryonic stage 11
      precursor cell of the stomatogastric nervous system
      (Hu et al., 1995)
      epidermis | segmentally repeated
      (Hu et al., 1995)
      embryonic stage 12
      epidermis | uniform
      (Hu et al., 1995)
      embryonic stage 12 -- 15
      rostral vesicle of iSNSP
      (Hartenstein et al., 1994)
      caudal vesicle of iSNSP
      (Hartenstein et al., 1994)
      invaginating stomatogastric nervous system precursor
      (Hartenstein et al., 1994)
      intermediate vesicle of iSNSP
      (Hartenstein et al., 1994)
      embryonic stage 14
      ventral midline of embryo
      (Hu et al., 1995)
      embryonic stage 15 -- 16
      embryonic hypocerebral ganglion
      (Hartenstein et al., 1994)
      embryonic proventricular ganglion
      (Hartenstein et al., 1994)
      embryonic frontal ganglion
      (Hartenstein et al., 1994)
      paraesophageal ganglion
      (Hartenstein et al., 1994)
      embryonic/larval hypocerebral ganglion
      (Hartenstein et al., 1994)
      embryonic stage 17
      visceral muscle fiber
      (Hu et al., 1995)
      larval stage
      eye-antennal disc | restricted
      (Hu et al., 1995)
      wing disc | restricted
      (Hu et al., 1995)
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      embryonic stage 10 -- 17
      invaginating stomatogastric nervous system precursor
      (Hartenstein et al., 1996)
      embryonic stage 11 -- 17
      embryonic epidermis
      (Tepass and Knust, 1993)
      intermediate vesicle of iSNSP
      (Hartenstein et al., 1996)
      caudal vesicle of iSNSP
      (Hartenstein et al., 1996)
      rostral vesicle of iSNSP
      (Hartenstein et al., 1996)
      Additional Information
      Statement
      Reference

      Expression resembles that of endogenous ab expression, as well as that of EcollacZab-BL97. Expression is observed in the midline of the CNS at embryonic stage 9, in the embryonic epidermis, and in syncytial muscle fibers .

      (Hu et al., 1995)

      Expression is observed beginning at embryonic stage 10 in the presumptive precursor cells of the stomatogastric nervous system. Intially, expression is homogeneous in the clypeo-labrum and the esophagus primordium. At stage 12, expression is observed in the invaginating stomatograstric nervous system precursor cells (iSNSPs) though not in the single ase-expressing tip stomatogastric nervous system precursor cell (tSNSP) which delaminates from each iSNSP pouch at the end of embryonic stage 12. Expression is lost in later stages in the delaminating stomatogastric nervous system precursor cells (dSNSPs).

      (Hartenstein et al., 1994)

      Expression is observed in epidermal cells from embryonic stage 11 until hatching.

      (Tepass and Knust, 1993)
       
      Marker for
      VUM precursor
      (Hu et al., 1995)
      invaginating stomatogastric nervous system precursor
      (Hartenstein et al., 1996, Hartenstein et al., 1994)
      stomatogastric nervous system
      (Hu et al., 1995)
      ventral midline of embryo
      (Hu et al., 1995)
      Reflects expression of
      ab
      (Hu et al., 1995)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Ecol\lacZab-94
      lacZab-94
      Name Synonyms
      Secondary FlyBase IDs
        References (4)