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General Information
Symbol
Ecol\lacZsd-ETX4
Species
E. coli
Name
FlyBase ID
FBal0041938
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
sd-lacZ, sd-LacZETX4
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Insertion components
P{lArB}sdETX4
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
No Assay Recorded
Stage
Tissue/Position (including subcellular localization)
Reference
distribution deduced from reporter
Stage
Tissue/Position (including subcellular localization)
Reference
dorsal medial indirect flight muscle
nucleus

Comment: reference states 21 hr APF

myoblast | subset
nucleus

Comment: myoblasts surrounding dorsal medial muscle; reference states 21 hr APF

Additional Information
Statement
Reference

Reporter expression is observed in some muscle cells at embryonic stage 13 including cardial cells and in almost all cardial cells in the heart region of the dorsal vessel and in some cardial cells in the aorta region in stage 16 embryos. It is also expressed in the hindgut.

Enhancer trap expression is first observed in embryos at stage 9 in cephalic neuroblasts. Expression continues weakly in the CNS throughout embryogenesis and includes sheath cells. Expression in the PNS is first observed at stage 11. By stage 14, intense staining is seen in ventral and lateral sense organs along the trunk and in the antennomaxillary complex. During head involution, intense staining is observed in the antennomaxillary complex and in the labral sense organs. In larvae, staining is observed in a restricted set of cells in the optic proliferation centers, the cerebral hemispheres and the ventral ganglion. The cells are probably not neuroblasts and may be glia or sheath cells. Enhancer trap staining is observed in all of the imaginal discs except the labial disc. Staining in the wing disc occurs in regions that will give rise to the adult wing blade, the scutellum, and the mesopleura. In the eye disc, staining is turned on immediately behind the morphogenetic furrow. In adults, enhancer trap expression is observed in discrete regions of the adult brain including cell bodies in the suboesophageal ganglion, nuclei lying medial to the antennal neuropile and within the lobular plate, cell bodies in the calyx of the mushroom bodies and cell bodies in the protocerebrum. Staining is also observed in the proboscis in two cells per sensillum that are thought to be the sheath cell and the glial cell. The sacculus and a subset of cells in the olfactory sensilla are stained as well as photoreceptor cells and restricted cells in the ventral ganglion. Finally, staining is observed in the jump muscle and in hairs located all over the adult cuticle.

 
Marker for
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (6)
Reported As
Symbol Synonym
Ecol\lacZsd-ETX4
lacZsd-ETX4
lacZsd-et
Name Synonyms
Secondary FlyBase IDs
  • FBal0041937
References (20)