Open Close
General Information
Symbol
Ecol\lacZsvp-AE127
Species
E. coli
Name
FlyBase ID
FBal0041984
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
AE127, svp-lacZ, svpAE127-lacZ
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

P-element insertion into the svp gene.

Insertion components
P{lwB}svpAE127
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
distribution deduced from reporter
Stage
Tissue/Position (including subcellular localization)
Reference
Additional Information
Statement
Reference

Ecol\lacZsvp-AE127 is expressed in seven segmentally repeated pairs of ostial cardioblasts.

Expression is observed in heart progenitors from embryonic stage 11. It is first observed in at least two cells per hemisegment in the posterior half of the embryo. From stage 12, expression observed in 4 strongly-expressing cardioblasts are seen in seven posterior segments in the embryo, with an additional pair of cells situated caudally to these and the pattern is maintained in stages 13-15. In stage 15, strong expression is observed in two adjacent pairs of cardioblasts in seven segments, plus another single pair located immediately poasterior to the last double pair of cardioblasts. The svp pattern is complementary to the tin pattern in that the two pairs of svp-expressing cardioblasts do not express tin. Expression is also observed at the anterior end of the dorsal vessel in cells that will become the corpus allatum and weakly in some pericardial cells.

 
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhancer of
Statement
Reference
Phenotype Manifest In
Enhancer of
Statement
Reference
Other
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference

The overall decrease in the number of cardioblasts in SB0453 mutant embryos is not affected by Ecol\lacZsvp-AE127; however, ostial cardioblasts become absent while generic cardioblasts increase in number.

Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
Ecol\lacZsvp-AE127
lacZsvp-AE127
Name Synonyms
Secondary FlyBase IDs
    References (44)