FlyBase Allele Report: Dmel\CycE[k02514]

(Prokopenko et al., 2000, Ashburner et al., 1999, Ashburner et al., 1999.10.12, Prokopenko and Bellen, 1997.1.7, BDGP Project Members, 1994-1999)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal - all die during embryonic stage | recessive

(Kania et al., 1995)

some die during embryonic stage | recessive

(Kania et al., 1995)

viable

(Prokopenko and Bellen, 1997.1.7)

visible | recessive

(Ashburner et al., 1999, Prokopenko and Bellen, 1997.1.7)

Phenotype Manifest In

chordotonal organ | lateral

(Kania et al., 1995)

eye

(Prokopenko and Bellen, 1997.1.7)

eye (with CycE⁰⁵²⁰⁶)

(Prokopenko et al., 2000)

ommatidium (with CycE⁰⁵²⁰⁶)

(Prokopenko et al., 2000)

presumptive embryonic/larval peripheral nervous system

(Kania et al., 1995)

wing vein

(Prokopenko and Bellen, 1997.1.7)

wing vein (with CycE⁰⁵²⁰⁶)

(Prokopenko et al., 2000)

Detailed Description

Statement

Reference

CycE^k02514/CycE⁰⁵²⁰⁶ adult escapers are viable, but have rough eyes and wing venation defects.

(Prokopenko et al., 2000)

Flies transheterozygous for CycE⁰⁵²⁰⁶ and CycE^k02514 are viable but have rough eyes and wing venation defects.

(Prokopenko and Bellen, 1997.1.7)

Homozygous embryos exhibit crowding and elongation of the lateral chordotonal (Lch) neurons, the overall organisation of the PNS is altered.

(Kania et al., 1995)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

CycE⁰⁵²⁰⁶

(Prokopenko et al., 2000)

CycE^k05002a

(Prokopenko et al., 2000)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Kyoto

102228

y¹ w^67c23 ; P{lacW}CycE^k02514 / CyO

Notes on Origin

Discoverer

I. Kiss.

(BDGP Project Members, 1994-1999)

Comments

This allele was listed in the BDGP database as a lethal or sterile line during the period 1994-1999, but was discarded from the gene disruption project prior to the summary publication (FBrf0111489). Reasons for excluding lines from the collection described in FBrf0111489 include presence of more than one P insertion on the mutant chromosome, separation of lethality (or sterility) from the location of the insertion, and loss of lethality (or sterility) from the stock. Further information is available from http://www.fruitfly.org/bfd/ and from Dr. Spradling (spradling@mail1.ciwemb.edu).

Complements: esg⁰⁵⁷²⁹. Complements: esg^k08104.

(Prokopenko et al., 2000)

Insert stated (in error) to be at 26A. Lethality not revertible with excision of the P{lacW} insert.

(Kania et al., 1995)

External Crossreferences and Linkouts ( 4 )

Crossreferences

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

Synonyms and Secondary IDs (6)

Reported As

Symbol Synonym

25/14

(Prokopenko and Bellen, 1997.1.7, Kania et al., 1995)

CycE^25-14

(Ashburner et al., 1999.10.12)

CycE^k02514

fond^25-14

fond^k02514

(Prokopenko et al., 2000)

l(2)k02514^k02514

Name Synonyms

Secondary FlyBase IDs

FBal0064580

References (6)

Report Sections

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