FlyBase Allele Report: Dmel\SmD3[k09512]

General Information

Symbol

Dmel\SmD3^k09512

Species

D. melanogaster

Name

FlyBase ID

FBal0043101

Feature type

allele

Associated gene

Dmel\SmD3

Associated Insertion(s)

P{lacW}SmD3^k09512

Carried in Construct

Also Known As

95/12

Key Links

Genomic Maps

JBrowse

Allele class

loss of function allele

Mutagen

P-element activity

Nature of the Allele

Allele class

loss of function allele

(Salzberg et al., 1996)

Mutagen

P-element activity

(Kania et al., 1995)

Progenitor genotype

Associated Insertion(s)

P{lacW}SmD3^k09512

Cytology

Description

Insertion of a P{lacW} element.

(Kania et al., 1995)

Allele components

Component

Use(s)

Inserted element

P{lacW}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

2R:12,168,754..12,168,754 [-]

(Salzberg et al., 1996, Kania et al., 1995, BDGP Project Members, 1994-1999)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal - all die during embryonic stage | recessive

(Salzberg et al., 1996, Kania et al., 1995)

some die during embryonic stage | recessive

(Salzberg et al., 1996, Kania et al., 1995)

Phenotype Manifest In

embryonic visceral muscle cell

(Salzberg et al., 1996)

larval somatic muscle cell

(Salzberg et al., 1996)

presumptive embryonic/larval central nervous system

(Salzberg et al., 1996)

presumptive embryonic/larval peripheral nervous system

(Salzberg et al., 1996, Kania et al., 1995)

Detailed Description

Statement

Reference

Homozygous embryos exhibit loss of neurons.

(Kania et al., 1995)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

SmD3^k09540

(BDGP Project Members, 1994-1999)

SmD3^k13101

(BDGP Project Members, 1994-1999)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Kyoto

102712

y¹ w^67c23 ; P{lacW}SmD3^k09512 / CyO

Notes on Origin

Discoverer

I. Kiss.

Comments

Lethality not revertible with excision of the P{lacW} insert. P{lacW}SmD3^k09512 and P{lacW}SmD3^k09540 insertions might be members of the same cluster and not genuine alleles.

(Kania et al., 1995)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

95/12

(Salzberg et al., 1996, Kania et al., 1995)

SmD3^k09512

guf^P95-12

(Salzberg et al., 1996)

guf^k09512

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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