FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\MESK2k05623
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General Information
Symbol
Dmel\MESK2k05623
Species
D. melanogaster
Name
FlyBase ID
FBal0043389
Feature type
allele
Associated gene
Dmel\MESK2
Associated Insertion(s)
P{lacW}MESK2k05623
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Roch et al., 1998)
Progenitor genotype
Associated Insertion(s)
P{lacW}MESK2k05623
Cytology
Description

P{lacW} insertion in exon 1.

(Schnorr et al., 2001)
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Mutants exhibit visible disc abnormalities: discs are small. Clones induced in wild type discs are abnormal: clones are at a lower frequency than expected and are small. Clones in the wing cause wing vein thickening.

      (Roch et al., 1998)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      MESK2k05623/MESK2[+] is an enhancer of dorsal appendage phenotype of Ras85Dix12a

      (Schnorr et al., 2001)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Weak dominant enhancer of the Ras85Dix12a eggshell phenotype; 41-50% of dorsal appendages are wild type.

      (Schnorr et al., 2001)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      I. Kiss.

      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      56/23
      (Roch et al., 1998)
      MESK2k05623
      l(2)01467k05623
      (BDGP Project Members, 1994-1999)
      l(2)k05623
      (Schnorr et al., 2001)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)