FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Rab32unspecified
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General Information
Symbol
Dmel\Rab32unspecified
Species
D. melanogaster
Name
FlyBase ID
FBal0044150
Feature type
allele
Associated gene
Dmel\Rab32
Associated Insertion(s)
Carried in Construct
Also Known As
unspecified
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description

    FlyBase curator comment: this entry is used to capture phenotypic information when the particular allele (or allele combination) used by the author could not be determined but the context of the experiment suggests that the phenotype being described is some kind of loss of function.

    (FlyBase Curators, 2025-)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 1 )
        Disease
        Evidence
        References
        model of  Parkinson's disease
        CEA
        (Macleod et al., 2013)
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        30 day old homozygotes show loss of dorsomedial posterior protocerebral and dorsolateral posterior protocerebral dopaminergic neurons compared to controls.

        (Macleod et al., 2013)

        ltdunspecified disrupts the change in sleep need in socially enriched adults after exposure to social impoverishment.

        (Ganguly-Fitzgerald et al., 2006)

        Eye colour: yellowish pink.

        (Hilliker and Holm, 1975)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Enhanced by
        Statement
        Reference

        Rab32unspecified has abnormal eye color phenotype, enhanceable by Df(1)N-8/we(g)

        (Lloyd et al., 2002)
        Phenotype Manifest In
        Enhanced by
        Statement
        Reference

        Rab32unspecified has pigment cell phenotype, enhanceable by Df(1)N-8/we(g)

        (Lloyd et al., 2002)
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        Female ltdunspecified/ltdunspecified; we(g)/Df(1)N-8 mutant flies have reduced levels of both red and brown pigment in the eye compared to ltdunspecified single mutants.

        (Lloyd et al., 2002)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Rescued by

        Rab32unspecified is rescued by Scer\GAL4ple.PF/Rab32UASp.YFP

        (Macleod et al., 2013)
        Comments

        Expression of ltdScer\UAS.P\T.T:Avic\GFP-YFP under the control of Scer\GAL4ple.PF rescues the loss of dorsomedial posterior protocerebral and dorsolateral posterior protocerebral dopaminergic neurons seen in 30 day old ltdunspecified homozygotes.

        (Macleod et al., 2013)
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        Comments
        Comments

        The distribution of ry protein in the tissues of the adult fly is altered in this mutant.

        (Reaume et al., 1991)
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (4)
        Reported As
        Symbol Synonym
        Rab32unspecified
        ltd
        (Lloyd et al., 2002)
        ltdunspecified
        unspecified
        (Silva et al., 1991, Hilliker and Holm, 1975)
        Name Synonyms
        Secondary FlyBase IDs
          References (7)