FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\elav339
Open Close
General Information
Symbol
Dmel\elav339
Species
D. melanogaster
Name
FlyBase ID
FBal0045581
Feature type
allele
Associated gene
Dmel\elav
Associated Insertion(s)
Carried in Construct
P{339}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Samson, 1998, Samson et al., 1995)
Progenitor genotype
Carried in construct
P{339}
Cytology
Description

Genomic DNA corresponding 7.5kb of the elav locus, including the ORF and 5.9kb of 5' sequences, with the insertion of a 12bp oligonucleotide between nucleotides 8650 and 8657, fused to 800bp of αTub84B trailer sequences. This mutation shortens the 74 amino acid ORF (downstream of ORF1) by 6 amino acids and splits the 131 amino acid ORF into a series of short ORFs.

(Samson et al., 1995)
Allele components
Component
Use(s)
Regulatory region(s)
elav
Encoded product / tool
elav
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      A single copy of elav339 has no deleterious effect on flies. The viability of flies carrying two copies of elav339 is very reduced and any escapers are sterile.

      (Samson, 1998)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      elav339 rescues elav5

      (Samson, 1998)

      elav339 rescues elavunspecified

      (Samson et al., 1995)
      Comments

      Rescues elav null mutants.

      (Samson et al., 1995)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      elav339
      Name Synonyms
      Secondary FlyBase IDs
        References (2)