loss of function allele
Molecular analysis reveals a deficiency that removes the scw transcript.
dorsal ectoderm (with scwE1)
embryo | embryonic stage 14 (with scwE1)
Not enhanced by Df(2R)Pcl11B.
Lethal when transheterozygous with scw- mutations. Transheterozygotes with scwE1 exhibit complete failure of head involution, internalised posterior structures and reduction in the amount of dorsal ectoderm. Mutation no longer interacts with dpphr4.