FlyBase Allele Report: Dmel\tsg[unspecified]

General Information

Symbol

Dmel\tsg^unspecified

Species

D. melanogaster

Name

FlyBase ID

FBal0046622

Feature type

allele

Associated gene

Dmel\tsg

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Cytology

Description

FlyBase curator comment: this entry is used to capture phenotypic information when the particular allele (or allele combination) used by the author could not be determined but the context of the experiment suggests that the phenotype being described is some kind of loss of function.

(FlyBase Curators, 2025-)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal - all die during embryonic stage | recessive

(Tearle and Nusslein-Volhard, 1987)

some die during embryonic stage | recessive

(Tearle and Nusslein-Volhard, 1987)

Phenotype Manifest In

amnioserosa

(Yu et al., 2000)

embryo

(Tearle and Nusslein-Volhard, 1987)

salivary gland

(Lammel and Saumweber, 2000, Lammel et al., 2000)

Detailed Description

Statement

Reference

Salivary glands are bent and in an abnormal position in mutant embryos and are often not internalised.

(Lammel and Saumweber, 2000)

Salivary glands in this mutant are abnormally placed.

(Lammel et al., 2000)

Mutant embryos lack amnioserosa cells.

(Yu et al., 2000)

The dorsal cells and posterior midgut are in an abnormal position at the extended germband stage in homozygous embryos.

(Zusman et al., 1988)

Gastrulation is abnormal in tsg^unspecified mutant embryos, similar to weak ventralising mutations.

(Tearle and Nusslein-Volhard, 1987)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Suppressed by

Statement

Reference

tsg^unspecified has amnioserosa phenotype, suppressible | partially by sog^hs.PY

(Yu et al., 2000)

tsg^unspecified has amnioserosa phenotype, suppressible | partially by sog^supersog1.hs

(Yu et al., 2000)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

tsg^unspecified is rescued by tsg^+t9.3

(Konrad et al., 1998)

tsg^unspecified is rescued by tsg^+t10.2

(Konrad et al., 1998)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

tsg^-

(Umulis et al., 2006)

tsg^unspecified

unspecified

(Zusman et al., 1988)

Name Synonyms

Secondary FlyBase IDs

References (9)

Report Sections

Open Close