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General Information
Symbol
Dmel\lilli4U5
Species
D. melanogaster
Name
FlyBase ID
FBal0049160
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

20bp deletion starting within the codon for amino acid residue T758, which results in the replacement of the original amino acid sequence with a shorter sequence with shifted reading frame.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 1 )
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Strong allele. The size of photoreceptor cells in homozygous clones in the eye is reduced compared to heterozygous cells adjacent to the clone. Mutant clones in the wing imaginal disc and in the eye disc anterior to the morphogenetic furrow are similar in size to their wild-type sister clones. Mutant clones posterior to the morphogenetic furrow are significantly smaller than their wild-type sister clones, although significant differences in cell death and mitosis are not seen between mutant and control clones. Generation of flies in which the eye imaginal disc is homozygous for lilli4U5 (using the "ey-Flp" system) results in flies in which the head and eyes are reduced compared to wild type. The reduction in eye size is caused by a reduction both in the number and size of ommatidia (24% and 18% respectively).

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressed by
Statement
Reference
Suppressor of
Statement
Reference
Phenotype Manifest In
Suppressor of
Statement
Reference

lilli4U5 is a suppressor of eye phenotype of Raf::tor12D.hs.sev

Other
Additional Comments
Genetic Interactions
Statement
Reference

Heads that are doubly mutant for Pten117 and lilli4U5 are smaller than those of Pten117 single mutants and wild-type flies.

Dominantly suppresses the rough eye phenotype of phl::tor12D.hs.sev.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (4)