FlyBase Allele Report: Dmel\TfIIA-S[E73]

General Information

Symbol

Dmel\TfIIA-S^E73

Species

D. melanogaster

Name

FlyBase ID

FBal0049212

Feature type

allele

Associated gene

Dmel\TfIIA-S

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

hypomorphic allele - genetic evidence

Mutagen

Delta2-3 transposase

Nature of the Allele

Allele class

hypomorphic allele - genetic evidence

(Zeidler et al., 1996)

Mutagen

Delta2-3 transposase

(Zeidler et al., 1996)

Progenitor genotype

P{FZ}Pli^F125

(Zeidler et al., 1996)

Cytology

Description

Generated by imprecise excision of P{FZ}F125. Deletion of all genomic DNA between the site of insertion of P{FZ}F125 (1.6kb 3' to the TfIIA-S coding region) and the 3' end of TfIIA-S.

(Zeidler et al., 1996)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal - all die before end of P-stage | recessive

(Zeidler et al., 1996)

some die during pharate adult stage | recessive

(Zeidler et al., 1996)

Phenotype Manifest In

eye

(Zeidler et al., 1996)

photoreceptor cell R1

(Zeidler et al., 1996)

photoreceptor cell R6

(Zeidler et al., 1996)

photoreceptor cell R7

(Zeidler et al., 1996)

photoreceptor neuron

(Zeidler et al., 1996)

Detailed Description

Statement

Reference

In the developing eye, defects in photoreceptor number, identity and position are apparent. R1 or R6 are often missing and R7 cells duplicated, suggesting transformation towards R7 cell identity.

(Zeidler et al., 1996)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Suppressor of

Statement

Reference

TfIIA-S^E73 is a suppressor of eye phenotype of Ras85D^V12.sev

(Zeidler et al., 1996)

TfIIA-S^E73 is a suppressor of eye phenotype of Raf::tor^12D.hs.sev

(Zeidler et al., 1996)

TfIIA-S^E73 is a suppressor of eye phenotype of rl^Sem

(Zeidler et al., 1996)

TfIIA-S^E73 is a suppressor of eye phenotype of sev^S11.Tag:MYC

(Zeidler et al., 1996)

TfIIA-S^E73 is a suppressor of eye phenotype of svp^2.sev

(Zeidler et al., 1996)

Additional Comments

Genetic Interactions

Statement

Reference

Suppresses the rough eye phenotype of sev^{S11.T:Hsap\MYC}, phl::tor^12D.hs.sev, Ras85D^V12.sev, rl^Sem and svp^2.sev.

(Zeidler et al., 1996)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

TfIIA-S^E73 is rescued by TfIIA-S^+t4

(Zeidler et al., 1996)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

5436

w^*; P{neoFRT}82B TfIIA-S^E73/TM6B, Tb¹

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

TfIIA-S^E73

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

Open Close