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General Information
Symbol
Dmel\gcm34
Species
D. melanogaster
Name
FlyBase ID
FBal0049596
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
glide/gcm34
Key Links
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Cytology
Nature of the lesion
Statement
Reference
Insertion components
P{lacZ}gcm34
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

gcm34 homozygous clones within mosaic spermathecae contain lumen epithelial cells, but completely lack secretory cells.

The INKA cell (a peptidergic, non-neuronal cell) can not be detected in most peritracheal cell clusters in homozygous embryos, whereas the other peritracheal cells remain detectable.

The INKA cell (a peptidergic, non-neuronal cell) can not be detected in most peritracheal cell clusters in gcm34/Df(2L)132 embryos, and in some cases other peritracheal cells in the cluster can not be detected.

In gcmN7-4/gcm34 embryos many glioblasts are transformed into neuroblasts.

gcmN7-4/gcm34 embryos have fewer hemocytes than normal, and the hemocytes show little migration compared to wild-type.

Homozygous embryos exhibit a drastic reduction in the number of glial cells. Studies of homozygotes and transheterozygotes with gcmN7-4 demonstrate most or all glial cells are transformed into neurons. Longitudinal fibres are partially or completely interrupted in several segments and the peripheral nerves exhibit defects.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (6)