FlyBase Allele Report: Dmel\rux[unspecified]

General Information

Symbol

Dmel\rux^unspecified

Species

D. melanogaster

Name

FlyBase ID

FBal0051197

Feature type

allele

Associated gene

Dmel\rux

Associated Insertion(s)

Carried in Construct

Also Known As

unspecified

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Cytology

Description

FlyBase curator comment: this entry is used to capture phenotypic information when the particular allele (or allele combination) used by the author could not be determined but the context of the experiment suggests that the phenotype being described is some kind of loss of function.

(FlyBase Curators, 2025-)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal locomotor behavior

(Vosshall and Young, 1995)

viable

(Price et al., 2002)

Phenotype Manifest In

Detailed Description

Statement

Reference

Displays locomotor activity rhythm with an approximately 24h period.

(Vosshall and Young, 1995)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

rux^unspecified/rux[+] is a suppressor of visible phenotype of CycE^JP

(Brumby et al., 2004)

Other

Statement

Reference

Wee1^unspecified, rux^unspecified has lethal phenotype

(Price et al., 2002)

Wee1^unspecified, rux^unspecified has Minute phenotype

(Price et al., 2002)

CycA^hs.PK, rux^unspecified has increased occurrence of cell division | embryonic stage phenotype

(Sprenger et al., 1997)

Phenotype Manifest In

Suppressed by

Statement

Reference

rux^unspecified has phenotype, suppressible by CycA⁵

(Gonczy et al., 1994)

rux^unspecified has phenotype, suppressible by twe¹

(Gonczy et al., 1994)

Enhancer of

Statement

Reference

rux^unspecified is an enhancer of eye phenotype of Wee1^unspecified

(Price et al., 2002)

Suppressor of

Statement

Reference

rux^unspecified/rux[+] is a suppressor of eye phenotype of CycE^JP

(Brumby et al., 2004)

Other

Statement

Reference

Wee1^unspecified, rux^unspecified has chaeta phenotype

(Price et al., 2002)

CycA^hs.PK, rux^unspecified has embryonic epidermis phenotype

(Sprenger et al., 1997)

Additional Comments

Genetic Interactions

Statement

Reference

wee rux double mutants (in which the wee and rux alleles are viable as single mutants) show almost complete synthetic lethality. Rare escapers show enhancement of the rux rough eye mutant phenotype, and have bristle duplications, deletions and "Minute" bristles.

(Price et al., 2002)

Expression of CycA^hs.PK using a 10 minute heat shock induces S phase in epidermal cells of rux^unspecified embryos carrying a single copy of CycA^hs.PK, but does not induce S phase in epidermal cells of wild-type embryos carrying a single copy of CycA^hs.PK.

(Sprenger et al., 1997)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

rux^unspecified

unspecified

(Sprenger et al., 1997, Vosshall and Young, 1995)

Name Synonyms

Secondary FlyBase IDs

References (6)

Report Sections

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