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General Information
Symbol
Dmel\mirrB1-12
Species
D. melanogaster
Name
FlyBase ID
FBal0051410
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

5' end of the cDNA is approximately 400bp apart from the P{lacW} insertion.

Insertion components
P{lacW}mirrB1-12
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

mirrB1-12/mirrg14 females lay normal eggs, 100% of which hatch. mirrP1/mirrB1-12 females lay eggs with abnormal eggshells and small dorsal appendages (in 50% of cases), 100% of which hatch.

Rare adult escapers. Homozygotes that escape lethality exhibit mild bristle defects, but have normal alula. Postalar bristle and alula are not affected heterozygotes. Transheterozygotes with mirrSai1 or mirrSai2 are semi-lethal. Rare adults exhibit outheld wings, the alulae are completely missing and postalar bristles are missing. Transheterozygotes with mirrg14 or mirre48 survive to the adult stage ad also exhibit outheld wings, missing alulae and bristle defects. Transheterozygotes with Df(3L)iro-DFM1 are semi-lethal with rare escapers. Escapers show outheld wings, lack of alulae and deletion of the posterior supraalar bristle and/or anterior postalar bristle. Transheterozygotes with Tp(3;3)iro-1 are viable and show no obvious defects in the alula, but they do show deletion of presutural bristle and anterior postalar bristle.

Adults escape lethality at rate of <1%.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement
Reference

mirrB1-12 has visible phenotype, enhanceable by Mob1

Other
Statement
Reference
Phenotype Manifest In
Enhanced by
Statement
Reference

mirrB1-12 has mesothoracic bristle phenotype, enhanceable by Mob1

Other
Additional Comments
Genetic Interactions
Statement
Reference

In combination with Mob1 the alula are eliminated. In combination with Mob1, mirrB1-12/Tp(3;3)iro-1 transheterozygotes exhibit complete removal of the lateral macrobristles.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (12)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
l(3)69DaB1-12
Name Synonyms
Secondary FlyBase IDs
    References (10)