FlyBase Allele Report: Dmel\mwh[unspecified]

General Information

Symbol

Dmel\mwh^unspecified

Species

D. melanogaster

Name

FlyBase ID

FBal0056465

Feature type

allele

Associated gene

Dmel\mwh

Associated Insertion(s)

Carried in Construct

Also Known As

unspecified

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Cytology

Description

FlyBase curator comment: this entry is used to capture phenotypic information when the particular allele (or allele combination) used by the author could not be determined but the context of the experiment suggests that the phenotype being described is some kind of loss of function.

(FlyBase Curators, 2025-)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal planar polarity

(Yan et al., 2008, Taylor et al., 1998)

visible | adult stage | recessive | somatic clone

(Amin et al., 1999)

Phenotype Manifest In

trichome & adult head | dorsal | somatic clone

(Amin et al., 1999)

wing hair

(Yan et al., 2008, Cong et al., 2001, Taylor et al., 1998)

wing hair | cell autonomous | somatic clone | increased number

(Yan et al., 2008)

wing hair | increased number

(Yan et al., 2008)

Detailed Description

Statement

Reference

Wing hairs in the most anterior region of the wing point towards the anterior margin in mutants, as opposed to distally as in wild type. Most of the wing cells form three to five hairs and often, one or two of these hairs are very small.

The multiple wing hair phenotype is limited to the mutant cells in wings containing homozygous clones.

(Yan et al., 2008)

Homozygous clones have a multiple wing hair phenotype (3.54 hairs/cell).

(Cong et al., 2001)

Homozygous clones on the dorsal head cause a dramatic decrease in hair length, but no obvious appearance of multiple hair elements.

(Amin et al., 1999)

Double mutants of Vang^Tbs42, Vang^A3 or Vang^A5 with fz²⁴, dsh¹ in^unspecified and mwh^unspecified all showed hair polarity pattern typical of the fz-in group. Multiple hair cell phenotypes of the cell autonomous dsh, in and mwh mutants are epistatic to Vang. Show no interaction with the dominant wing basal cell 1 swirl phenotype of Vang^Tbs42.

(Taylor et al., 1998)

The frequency of mwh^unspecified-jv^unspecified clones produced by mitotic recombination during larval growth is greater in flies derived from crosses of mwh^unspecified jv^unspecified D.melanogaster females to D.melanogaster males than in flies derived from crosses of mwh^unspecified jv^unspecified D.melanogaster females to D.simulans males.

(Sanchez et al., 1994)

The degree of mosaicism of the mow¹ phenotype is increased if the fly is also heterozygous for mwh^unspecified.

(Konev, 1987)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

fry¹, mwh^unspecified has visible | somatic clone phenotype

(Cong et al., 2001)

Phenotype Manifest In

Other

Statement

Reference

fry¹, mwh^unspecified has wing hair | somatic clone phenotype

(Cong et al., 2001)

Mosaic^unspecified, mwh^unspecified has wing phenotype

(Vaisman and Zakharov, 1995)

Mosaic^unspecified, mwh^unspecified has scutellar bristle phenotype

(Vaisman and Zakharov, 1995)

Mosaic^unspecified, mwh^unspecified has dorsocentral bristle phenotype

(Vaisman and Zakharov, 1995)

Additional Comments

Genetic Interactions

Statement

Reference

mwh^unspecified fry¹ double mutant clones have a much stronger multiple wing hair phenotype (16.35 hairs/cell) than either single mutant.

(Cong et al., 2001)

In cis mwh^unspecified Mos^unspecified heterozygotes, the frequency of small mutant clones on the wing is increased. In trans mwh^unspecified/Mos^unspecified heterozygotes there is a significant reduction of dorsocentral and scutellar bristles.

(Vaisman and Zakharov, 1995)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

mwh^unspecified is rescued by Scer\GAL4^ap-md544/mwh^UAS.cYa

(Yan et al., 2008)

mwh^unspecified is rescued by Scer\GAL4^en-e16E/mwh^UAS.cYa

(Yan et al., 2008)

Partially rescued by

mwh^unspecified is partially rescued by Scer\GAL4^Act.PU/mwh^UAS.cYa

(Yan et al., 2008)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

CG43772^unspecified

mwh^unspecified

unspecified

(Ordaz-Tellez and Ramos-Morales, 1997, Olvera-Ramirez et al., 1996, Pimentel et al., 1996, Ramos-Morales and Gonzalez, 1996, Rodriguez-Arnaiz et al., 1996, Spano et al., 1996, Yoshikawa et al., 1996, Ramos-Morales and Rodriguez-Arnaiz, 1995, Ramos-Morales et al., 1995, Vaisman and Zakharov, 1995, de la Rosa et al., 1994, Marec and Gelbic, 1994, Ogawa et al., 1994, Sanchez et al., 1994, Zordan et al., 1994, Tripathy et al., 1993, Konev, 1987)

Name Synonyms

Secondary FlyBase IDs

References (94)

Report Sections

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