FB2026_02 , released June 18, 2026
Allele: Dmel\PolQSz29
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General Information
Symbol
Dmel\PolQSz29
Species
D. melanogaster
Name
FlyBase ID
FBal0056466
Feature type
allele
Associated gene
Dmel\PolQ
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Caused by aberration
    Df(3R)kar-Sz29
    Cytology
    Description

    Distal deficiency breakpoint breaks within exon 4.

    (Harris et al., 1996)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Studies of excision and repair events of P{hswa} in mus308D2/mus308Sz29 or mus308D5/mus308Sz29 males indicate that DNA repair synthesis during synthesis-dependent strand annealing (SDSA) is unaffected in the mutants but that the mutants are defective in end-joining repair of DNA double-strand breaks.

        Studies of excision and repair events of P{hswa} in mus308ZIII-2003/mus308Sz29 or mus308ZIII-3294/mus308Sz29 males indicate that they are specifically defective in end-joining repair of DNA double-strand breaks.

        (Chan et al., 2010)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (4)
        Reported As
        Symbol Synonym
        DNApol-θSz29
        PolQSz29
        mus308Sz-29
        (Yu and McVey, 2010)
        mus308Sz29
        Name Synonyms
        Secondary FlyBase IDs
          References (3)