FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\ciZn:AD.UAS.Tag:MYC
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General Information
Symbol
Dmel\ciZn:AD.UAS.Tag:MYC
Species
D. melanogaster
Name
FlyBase ID
FBal0057700
Feature type
allele
Associated gene
Dmel\ci
Associated Insertion(s)
Carried in Construct
P{UAS-ciZn/GAL4AD}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Hepker et al., 1997)
Progenitor genotype
ciZn.UAS.Tag:MYC
(Hepker et al., 1997)
Carried in construct
P{UAS-ciZn/GAL4AD}
Cytology
Description

The activation domain of Scer\GAL4 (amino acids 768-881) is fused in frame to the ci coding region of ciZn.UAS.Tag:MYC which includes the ci initiator ATG and amino acids 440-684, (hence the zinc finger domain). Expression is governed by UASt regulatory sequences.

(Hepker et al., 1997)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
ci
Tagged with
Tag:MYC
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      ciZn:AD.Scer\UAS.T:Hsap\MYC,T:Scer\GAL4; Scer\GAL4h-H10 and ciZn:AD.Scer\UAS.T:Hsap\MYC,T:Scer\GAL4; Scer\GAL4fng-B flies have normal eyes.

      (Fu and Baker, 2003)

      When expression is governed by Scer\GAL4en-e16E, adults survive with disrupted posterior wing veins, similar to that observed for ci1 and ciW.

      (Hepker et al., 1997)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4prd.RG1/ciZn:AD.UAS.Tag:MYC rescues ciCe-1

      (Hepker et al., 1997)
      Comments

      ciZn:AD.Scer\UAS.T:Hsap\MYC,T:Scer\GAL4 rescues the embryonic segmentation defect of ciCe-1 mutants, when expressed from Scer\GAL4prd.RG1.

      (Hepker et al., 1997)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      ci::GAL4Zn/AD.UAS.T:Myc
      ciZn/AD.Scer\UAS.T:Hsap\MYC,T:Scer\GAL4
      ciZn:AD.Scer\UAS.T:Hsap\MYC,T:Scer\GAL4
      ciZn:AD.UAS.Tag:MYC
      Name Synonyms
      Secondary FlyBase IDs
        References (2)