FlyBase Allele Report: Dmel\sog[P129D]

General Information

Symbol

Dmel\sog^P129D

Species

D. melanogaster

Name

suppressor

FlyBase ID

FBal0059935

Feature type

allele

Associated gene

Dmel\sog

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal (with sog^P1)

(Serpe et al., 2005)

lethal (with sog^YL26)

(Serpe et al., 2005)

viable

(Serpe et al., 2005, Decotto and Ferguson, 2001, Rosen and Ferguson, 1997)

Phenotype Manifest In

posterior crossvein (with sog^P1)

(Serpe et al., 2005)

posterior crossvein (with sog^YL26)

(Serpe et al., 2005)

Detailed Description

Statement

Reference

31% of sog^P129D/sog^YL26 flies survive to adulthood. Of these, 15% exhibit partial loss of the posterior crossvein and the rest show more subtle alterations in which the posterior crossvein appears as a fragmented line. Only 12% of sog^P129D/sog^P1 transheterozygotes survive to adulthood and 46% of these exhibit various degrees of loss of the posterior crossvein.

(Serpe et al., 2005)

80% of homozygous embryos survive to adulthood.

(Decotto and Ferguson, 2001)

Homozygous viable, few flies transheterozygous with lethal sog alleles survive.

(Ferguson and Anderson, 1992)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

sog^P129D has lethal | recessive | partially phenotype, enhanceable by Mad^ES1/Mad[+]

(Decotto and Ferguson, 2001)

sog^P129D has lethal | recessive | partially phenotype, enhanceable by Mad¹²/Mad[+]

(Decotto and Ferguson, 2001)

sog^P129D has lethal | recessive | partially phenotype, enhanceable by Med¹³/Med[+]

(Decotto and Ferguson, 2001)

sog^P129D has lethal | recessive | partially phenotype, enhanceable by Med[+]/Med¹⁵

(Decotto and Ferguson, 2001)

sog^P129D has lethal | recessive | partially phenotype, enhanceable by Med[+]/Med^ES3

(Decotto and Ferguson, 2001)

sog^P129D has lethal | recessive | partially phenotype, enhanceable by Med[+]/Med^ES2

(Decotto and Ferguson, 2001)

Other

Statement

Reference

sog^P129D, zen¹ has lethal | recessive | embryonic stage phenotype

(Decotto and Ferguson, 2001)

Phenotype Manifest In

Suppressor of

Statement

Reference

sog^YL26/sog^P129D is a suppressor of crossvein phenotype of tok^Δ2-41/tok^E1

(Serpe et al., 2005)

sog^P129D is a suppressor of phenotype of tld^unspecified

(Ferguson and Anderson, 1992)

Other

Statement

Reference

Mad^ES1/Mad[+], sog^P129D has filzkorper phenotype

(Decotto and Ferguson, 2001)

Mad^ES1/Mad[+], sog^P129D has embryonic head phenotype

(Decotto and Ferguson, 2001)

Mad^ES1/Mad[+], sog^P129D has amnioserosa phenotype

(Decotto and Ferguson, 2001)

sog^P129D, zen¹ has embryonic/first instar larval cuticle phenotype

(Decotto and Ferguson, 2001)

Mad^ES1, sog^P129D has filzkorper phenotype

(Decotto and Ferguson, 2001)

Mad^ES1, sog^P129D has embryonic head phenotype

(Decotto and Ferguson, 2001)

Mad^ES1, sog^P129D has amnioserosa phenotype

(Decotto and Ferguson, 2001)

Additional Comments

Genetic Interactions

Statement

Reference

sog^YL26/+; tok^Δ2-41/tok^E1 escapers exhibit partial posterior crossveins with significantly more crossvein material than tok^Δ2-41/tok^E1 escapers. Further, crossveins are almost completely restored in sog^YL26/sog^P129D; tok^Δ2-41/tok^E1 animals.

(Serpe et al., 2005)

Only 39% of sog^P129D/+ embryos derived from Mad^ES1/+ females survive to adulthood. sog^P129D embryos derived from Mad^ES1/+ females have internalised filzkorper and lack head elements, indicative of weak ventralisation. The amnioserosa is reduced. sog^P129D ; zen¹ double mutant embryos die with a partially ventralised phenotype at 25^oC.

(Decotto and Ferguson, 2001)

Suppressor of the tld mutant phenotype but not of the dpp mutant phenotype.

(Ferguson and Anderson, 1992)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

Weak sog mutation.

(Rosen and Ferguson, 1997)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

sog^P129D

(Matsuda et al., 2013, Matsuda and Shimmi, 2012)

sog^supp

Name Synonyms

suppressor

(Ferguson and Anderson, 1992)

Secondary FlyBase IDs

FBal0046506

References (6)

Report Sections

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