FlyBase Allele Report: Dmel\ftz-f1[ex17]

General Information

Symbol

Dmel\ftz-f1^ex17

Species

D. melanogaster

Name

FlyBase ID

FBal0060400

Feature type

allele

Associated gene

Dmel\ftz-f1

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Cytology

Description

A deletion that removes ftz-f1 regulatory sequences.

(Woodard and McCabe, 1997)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal (with Df(3L)Cat)

(Beckstead et al., 2001)

lethal - all die before end of pupal stage | recessive

(Woodard and McCabe, 1997)

partially lethal | recessive

(Beckstead et al., 2001)

some die during pupal stage | recessive

(Woodard and McCabe, 1997)

visible (with Df(3L)Cat)

(Beckstead et al., 2001)

Phenotype Manifest In

adult head (with Df(3L)Cat)

(Beckstead et al., 2001)

head | P-stage

(Woodard and McCabe, 1997)

leg (with Df(3L)Cat)

(Beckstead et al., 2001)

leg | P-stage

(Woodard and McCabe, 1997)

pupal cuticle

(Woodard and McCabe, 1997)

Detailed Description

Statement

Reference

38% of ftz-f1^ex17/Df(3L)Cat animals die as pharate adults with short malformed legs, 45% undergo head eversion but arrest early in pupal development and 17% fail to undergo head eversion but continue developing into cryptocephalic pharate adults. 31% of homozygotes survive as adult escapers.

(Beckstead et al., 2001)

Head eversion, pupal cuticle formation and leg evagination fail.

(Woodard and McCabe, 1997)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

ftz-f1^ex17/Df(3L)Cat has lethal phenotype, suppressible | partially by bon^S024108/bon[+]

(Beckstead et al., 2001)

ftz-f1^ex17/Df(3L)Cat has lethal phenotype, suppressible | partially by bon^S048706/bon[+]

(Beckstead et al., 2001)

ftz-f1^ex17 has partially lethal | recessive phenotype, suppressible by bon^S048706/bon[+]

(Beckstead et al., 2001)

ftz-f1^ex17 has partially lethal | recessive phenotype, suppressible by bon^S024108/bon[+]

(Beckstead et al., 2001)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Most ftz-f1^ex17/Df(3L)Cat animals are rescued to the pharate adult stage by one copy of bon^S048706 (87%) or bon^S024108 (70%). The number of homozygous ftz-f1^ex17 adult escapers is increased by one copy of bon^S048706 (72%) or bon^S024108 (60%).

(Beckstead et al., 2001)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

ex17

(Woodard and McCabe, 1997)

ftz-f1^ex17

βFTZ-F1^ex17

(Beckstead et al., 2001)

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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