UASt regulatory sequences drive expression of a 1.1kb EcoRI-XbaI fragment containing the 5' untranslated region and coding sequence of rux.
abnormal size | larval stage, with Scer\GAL4prd.RG1
decreased occurrence of cell division | larval stage, with Scer\GAL4prd.RG1
eye disc | larval stage, with Scer\GAL4prd.RG1
nucleus | larval stage, with Scer\GAL4prd.RG1
wing disc | larval stage, with Scer\GAL4prd.RG1
Scer\GAL4prd.RG1-mediated expression in wild type flies blocks mitosis and increases the nuclei size (consist with inducing endoreplication). Similar phenotype is exhibited in the wing disc from Scer\GAL430A-mediated expression.
Scer\GAL4prd.RG1-mediated expression of ruxScer\UAS.cTa in the embryonic somatic cells of CycEhs.PR is unable to inhibit CycE-dependent processes, ectopic entry into S phase.