FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Dsor1Su12
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General Information
Symbol
Dmel\Dsor1Su12
Species
D. melanogaster
Name
FlyBase ID
FBal0061976
Feature type
allele
Associated gene
Dmel\Dsor1
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description

    Amino acid replacement: M159L.

    (Lim et al., 1997)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    point_mutation
    X:9,248,915..9,248,915 [+]
    Nucleotide change:

    A9248915C

    Amino acid change:

    M162L | Dsor1-PA; M159L | Dsor1-PB

    Reported amino acid change:

    M159L

    Comment:

    Reported as M159L in FBrf93573. Maps to M162L in the CDS encoded by the reference sequence. The difference is due to the use of an upstream splice acceptor in an upstream intron. The annotated version is supported by full length cDNA LD41207 (GB:AY058692). The site of the nucleotide substitution in the mutant was inferred by FlyBase based on the reported amino acid change.

    (Lim et al., 1997)
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        The number of R7-like cells per ommatidium is slightly increased in homozygotes compared to wild-type flies.

        (Lim et al., 1997)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Suppressor of
        Statement
        Reference

        Dsor1Su12 is a suppressor of phenotype of Raf1

        (Lim et al., 1997)

        Dsor1Su12 is a suppressor of phenotype of sev6

        (Lim et al., 1997)

        Dsor1Su12 is a suppressor of phenotype of tor4

        (Lim et al., 1997)
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        Almost completely suppresses the eye phenotype of phl1 hemizygotes; 99.0% of ommatidia are normal in phl1 hemizygotes also carrying Dsor1Su12. Partly suppresses the sev6 phenotype; flies hemizygous for sev6 and Dsor1Su12 have an R7 photoreceptor cell in 3.1% of ommatidia. Partly suppresses the maternal tor4 phenotype; 27.7% of embryos derived from tor4 Dsor1Su12 females have an A8 segment.

        (Lim et al., 1997)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        Dsor1Su12
        Name Synonyms
        Secondary FlyBase IDs
          References (1)