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General Information
Symbol
Dmel\srUAS.cBa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Becker
FlyBase ID
FBal0062432
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

A 4.5kb EcoRI fragment of srB cDNA is expressed under the control of UASt regulatory sequences.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

When srScer\UAS.cBa is driven by Scer\GAL469B the number of cells that migrate into the dorsal branch of the tracheal system is increased - normally 5 to 6 cells are allocated, but this increases to up to ten in mutants. Terminal branch specification is unaffected.

When srScer\UAS.cBa is expressed in the salivary glands (using Scer\GAL4sim.PS) in Df(3R)DG4/+ embryos, the lateral somatic myotubes are attracted to the salivary glands and adhere to them (in contrast to wild-type where they do not attach to the salivary glands). Myotubes are also attracted to cells expressing srScer\UAS.cBa under the control of Scer\GAL4ptc-559.1 in Df(3R)DG4/+ embryos. Embryos expressing srScer\UAS.cBa under the control of Scer\GAL4en-e16E or Scer\GAL4ptc-559.1 in a wild-type background have mild aberrations in the somatic muscle pattern; some myotubes may be missing, others are oriented abnormally and may be connected to the cells expressing srScer\UAS.cBa, and the lateral transverse muscles often show abnormal morphology. Homozygous srG11 embryos that are expressing srScer\UAS.cBa under the control of Scer\GAL4en-e16E show a severe disruption of the somatic muscle pattern, especially that of the lateral transverse muscles.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Enhancer of
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

When srScer\UAS.cBa and bnlScer\UAS.cSa are both driven by Scer\GAL4sim.PS a dramatic tracheal sprouting is seen in the salivary glands, showing an enhancement of the bnlScer\UAS.cSa, Scer\GAL4sim.PS phenotype.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
srScer\UAS.cBa
srUAS.cBa
Name Synonyms
Saccharomyces cerevisiae UAS construct a of Becker
Secondary FlyBase IDs
    References (7)