FlyBase Allele Report: Dmel\mew[UAS.cMBb]

General Information

Symbol

Dmel\mew^UAS.cMBb

Species

D. melanogaster

Name

Saccharomyces cerevisiae UAS construct b of Martin-Bermudo

FlyBase ID

FBal0062566

Feature type

allele

Associated gene

Dmel\mew

Associated Insertion(s)

Carried in Construct

P{UAS-mew.c/g}

Key Links

Transgenic product class

wild_type

(Martin-Bermudo et al., 1997)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Martin-Bermudo et al., 1997)

Mutagen

in vitro construct

(Martin-Bermudo et al., 1997)

Progenitor genotype

Carried in construct

P{UAS-mew.c/g}

Cytology

Description

mew is expressed under the control of UAS regulatory sequences. The mew coding sequences are a fusion of genomic and cDNA sequences (the first 44 amino acids are encoded by cDNA sequence, and the rest of the protein is encoded by genomic sequence).

(Martin-Bermudo et al., 1997)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

mew

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

mys^UAS.cDa, mew^UAS.cMBb, Scer\GAL4^ppk.PG is a suppressor of abnormal neuroanatomy | larval stage phenotype of fne^KOZ40

(Alizzi et al., 2020)

Scer\GAL4^twi.PG, Scer\GAL4^how-24B, mew^UAS.cMBb is a suppressor of lethal | recessive | embryonic stage phenotype of if^B4

(Martin-Bermudo et al., 1997)

NOT Suppressor of

Statement

Reference

Scer\GAL4^how-24B/mew^UAS.cMBb is a non-suppressor of lethal | recessive | embryonic stage phenotype of if^B4

(Martin-Bermudo et al., 1997)

Phenotype Manifest In

Suppressor of

Statement

Reference

mys^UAS.cDa, mew^UAS.cMBb, Scer\GAL4^ppk.PG is a suppressor of larval multidendritic class IV neuron | larval stage phenotype of fne^KOZ40

(Alizzi et al., 2020)

mys^UAS.cDa, mew^UAS.cMBb, Scer\GAL4^ppk.PG is a suppressor of dendritic branch | larval stage phenotype of fne^KOZ40

(Alizzi et al., 2020)

mys^UAS.cDa, mew^UAS.cMBb, Scer\GAL4^ppk.PG is a suppressor of dendritic tree | larval stage phenotype of fne^KOZ40

(Alizzi et al., 2020)

Additional Comments

Genetic Interactions

Statement

Reference

The embryonic lethality of if^B4 homozygotes is not rescued by mew^{Scer\UAS.cMBb} expressed using Scer\GAL4^how-24B, although it is rescued in approximately 1/3 of cases by mew^{Scer\UAS.cMBb} expressed using Scer\GAL4^how-24B in conjunction with Scer\GAL4^twi.PG.

(Martin-Bermudo et al., 1997)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

mew^UAS.cMBb/Scer\GAL4^48Y rescues mew^M6

(Martin-Bermudo et al., 1997)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

mew^{Scer\UAS.cMBb}

mew^UAS.cMBb

Name Synonyms

Saccharomyces cerevisiae UAS construct b of Martin-Bermudo

(Martin-Bermudo et al., 1997)

Secondary FlyBase IDs

References (3)

Report Sections

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