FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\E(spl)m8-HLHΔbHLH.UAS
Open Close
General Information
Symbol
Dmel\E(spl)m8-HLHΔbHLH.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0063461
Feature type
allele
Associated gene
Dmel\E(spl)m8-HLH
Associated Insertion(s)
Carried in Construct
P{UAS-E(spl)m8-HLHΔbHLH}
Key Links
Transgenic product class
inframe_deletion
(Giebel and Campos-Ortega, 1997)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Giebel and Campos-Ortega, 1997)
Mutagen
in vitro construct
(Giebel and Campos-Ortega, 1997)
Progenitor genotype
Carried in construct
P{UAS-E(spl)m8-HLHΔbHLH}
Cytology
Description

UASt regulatory sequences drive expression of an E(spl)m8-HLH cDNA carrying a deletion of the HLH domain.

(Giebel and Campos-Ortega, 1997)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
E(spl)m8-HLH
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Scer\GAL4sca-537.4-mediated expression suppresses development of bristles on the notum and head and causes double socket formation of bristles on the abdomen.

      (Giebel and Campos-Ortega, 1997)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Strong reduction in the number of ectopic scutellar macrochaetes of strain ZB1.4 (activator insertion Scer\GAL4455.2 is combined with l(1)scScer\UAS.cHa).

      (Giebel and Campos-Ortega, 1997)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      E(spl)ΔbHLH.Scer\UAS
      E(spl)ΔbHLH.UAS
      E(spl)m8-HLHΔbHLH.Scer\UAS
      E(spl)m8-HLHΔbHLH.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (1)