FB2026_02 , released June 18, 2026
Allele: Dmel\sdETX81
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General Information
Symbol
Dmel\sdETX81
Species
D. melanogaster
Name
FlyBase ID
FBal0063782
Feature type
allele
Associated gene
Dmel\sd
Associated Insertion(s)
P{lArB}ETX81a
P{lArB}ETX81b
Carried in Construct
Key Links
Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Deshpande et al., 1997)
Mutagen
Delta2-3 transposase
(Anand et al., 1990)
P-element activity
(Deshpande et al., 1997)
Progenitor genotype
Associated Insertion(s)
P{lArB}ETX81a
P{lArB}ETX81b
Cytology
Description

One insertion in the 5' intron before the translation start and a second within a 2kb region located toward the 3' end of the gene.

(Deshpande et al., 1997)
Allele components
Component
Use(s)
Inserted element
P{lArB}
P{lArB}
Encoded product / tool
lacZ
lacZ
Tagged with
Tag:NLS(P)
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      sdETX81 mutants show significant increases in the mushroom body and the Kenyon cell cluster sizes, as compared to controls.

      (Rohith and Shyamala, 2017)

      The wing disc is distorted and there is a reduction in the size of the presumptive wing blade in hemizygous males.

      (Varadarajan and VijayRaghavan, 1999)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressed by
      Statement
      Reference

      sdETX81 has lethal phenotype, suppressible by Hsap\TEAD1hs.PD

      (Deshpande et al., 1997)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      sdETX81 animals carrying Hsap\TCF13hs.PD show adult emergence, these adults exhibit wing defects, roughened eye and maxillary palp phenotypes.

      (Deshpande et al., 1997)
      Complementation and Rescue Data
      Partially complements

      sdSG29.1

      (Shyamala and Chopra, 1999)
      Rescued by

      sdETX81 is rescued by sdhs.PC

      (Deshpande et al., 1997)
      Comments

      partially rescued by: sdhs.PC sdETX81 animals carrying sdhs.PC show adult emergence, these adults exhibit wing defects, roughened eye and maxillary palp phenotypes.

      (Deshpande et al., 1997)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Strong sd mutation.

      (Deshpande et al., 1997)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      sdETX81
      (Rohith and Shyamala, 2017)
      sdP(ry+,ETX81)
      (Varadarajan and VijayRaghavan, 1999)
      Name Synonyms
      Secondary FlyBase IDs
        References (5)