FlyBase Allele Report: Dmel\spen[k13624]

FB2026_01 , released March 12, 2026

FB2026_01 , released March 12, 2026

Allele: Dmel\spen^k13624

General Information

Symbol

Dmel\spen^k13624

Species

D. melanogaster

Name

FlyBase ID

FBal0064378

Feature type

allele

Associated gene

Associated Insertion(s)

P{lacW}spen^k13624

Carried in Construct

Key Links

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Roch et al., 1998, BDGP Project Members, 1994-1999)

Progenitor genotype

Associated Insertion(s)

P{lacW}spen^k13624

Cytology

Description

Insertion lies within a 4kb region that represents a hot spot for P-element insertions and maps ~20kb upstream from the Class I cDNA which includes the spen ORF, and immediately upstream of (and slightly overlaps) the j1 cDNA that likely corresponds to the spen 5' UTR.

(Rebay et al., 2000)

Allele components

Component

Use(s)

Inserted element

Encoded product / tool

reporter enzyme

Tagged with

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Roch et al., 1998)

Phenotype Manifest In

Detailed Description

Statement

Reference

Lethality occurs during third instar larval or pupal stages. Mutants do not show any visible disc abnormalities.

(Roch et al., 1998)

External Data

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

spen^k13624/spen^k07721 is a suppressor of visible phenotype of dpp^d-blk

(Lin et al., 2003)

Phenotype Manifest In

Suppressor of

Statement

Reference

spen^k13624/spen^k07721 is a suppressor of eye phenotype of dpp^d-blk

(Lin et al., 2003)

spen^k13624/spen^k07721 is a suppressor of photoreceptor neuron phenotype of dpp^d-blk

(Lin et al., 2003)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Complements

spen⁰³³⁵⁰

(BDGP Project Members, 1994-1999)

(BDGP Project Members, 1994-1999)

(BDGP Project Members, 1994-1999)

Fails to complement

(Lin et al., 2003)

(Lin et al., 2003)

spen^{E(Sev-CycE)2A}

(Lane et al., 2000)

spen^{E(Sev-CycE)E9}

(Lane et al., 2000)

(BDGP Project Members, 1994-1999)

(BDGP Project Members, 1994-1999)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

I. Kiss.

(BDGP Project Members, 1994-1999)

Comments

Comments

Complements: kis⁰⁷⁸¹². Complements: Rpp30^k01901.

(BDGP Project Members, 1994-1999)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

136/24

(Roch et al., 1998)

l(2)k07612^k13624

(BDGP Project Members, 1994-1999)

l(2)k13624

(Rebay et al., 2000)

spen^k13624

Name Synonyms

Secondary FlyBase IDs

References (6)

Report Sections