FlyBase Allele Report: Dmel\snRNA:U6atac[k01105]

(Connell et al., 2024, Praveen et al., 2012, Pessa et al., 2010, Otake et al., 2002, Spradling et al., 1999, Roch et al., 1998, BDGP Project Members, 1994-1999)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

decreased occurrence of cell division | larval stage

(Connell et al., 2024)

lethal (with Df(2L)ED611)

(Kahsai et al., 2016)

lethal | recessive

(Otake et al., 2002, Spradling et al., 1999, Roch et al., 1998)

Phenotype Manifest In

embryonic/larval crystal cell

(Milchanowski et al., 2004)

imaginal disc

(Roch et al., 1998)

larval brain | larval stage

(Connell et al., 2024)

Detailed Description

Statement

Reference

The average number of crystal cells per embryo is reduced (to 10.8) in homozygous stage 13-14 embryos compared to wild type (36 +/- 2.2 cells on average).

(Milchanowski et al., 2004)

Lethality occurs during third instar larval or pupal stages. Mutants exhibit visible disc abnormalities: very small or no discs. Clones induced in wild type discs are of normal size and shape.

(Roch et al., 1998)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Partially rescued by

snRNA:U6atac^k01105 is partially rescued by snRNA:U6atac^+t206

(Otake et al., 2002)

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

10492

y¹ w^67c23; P{lacW}snRNA:U6atac^k01105/CyO

Kyoto

114341

y^d2 w¹¹¹⁸ P{ey-FLP.N}2 P{5xglBS-lacZ.38-1}TPN1; P{lacW}snRNA:U6atac^k01105 P{neoFRT}40A/CyO y⁺

Notes on Origin

Discoverer

I. Kiss.

(BDGP Project Members, 1994-1999)

Comments

Complements: l(2)k12914^k12914. Complements: emb^k16715.

(BDGP Project Members, 1994-1999)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (7)

Reported As

Symbol Synonym

11/5

(Roch et al., 1998)

P10492

(Milchanowski et al., 2004)

U6atac^K01105

(Lotti et al., 2012)

l(2)k01105

(Pessa et al., 2010, Spradling et al., 1999)

l(2)k01105^k01105

(Otake et al., 2002, BDGP Project Members, 1994-1999)

snRNA:U6atac:29B^k01105

snRNA:U6atac^k01105

(Connell et al., 2024)

Name Synonyms

Secondary FlyBase IDs

References (10)

Report Sections

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