FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Allele: Dmel\Madk00223
Open Close
General Information
Symbol
Dmel\Madk00223
Species
D. melanogaster
Name
FlyBase ID
FBal0064631
Feature type
allele
Associated gene
Dmel\Mad
Associated Insertion(s)
P{lacW}Madk00223
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Roch et al., 1998, BDGP Project Members, 1994-1999)
Progenitor genotype
Associated Insertion(s)
P{lacW}Madk00223
Cytology
Description

The P{lacW}Madk00223 insertion affects both the gkt and Mad genes; it fails to complement both gkt and Mad mutant alleles.

(Dunlop et al., 2004)

The P{lacW} insertion is within the 5' untranslated region of Mad.

(Dunlop et al., 2000)
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Lethality occurs during third instar larval or pupal stages. Mutants exhibit visible disc abnormalities: discs are small. Clones induced in wild type discs are abnormal: altering cell differentiation.

      (Roch et al., 1998)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      I. Kiss.

      (BDGP Project Members, 1994-1999)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      2/23
      (Roch et al., 1998)
      Madk00223
      l(2)k00237k00223
      Name Synonyms
      Secondary FlyBase IDs
        References (5)