One copy of EcRQ50st has no effect on hemocyte proliferation in third instar larvae.
Mutants that lack EcR-B1 (e.g. EcRQ50st/EcR31) exhibit no difference in Crz-expressing ventral nerve cord neuronal cell death compared to wild-type.
Some EcRQ50st/EcRM554fs animals survive to the third larval instar stage, but they do not pupariate. They initiate wandering, but fail to evert spiracles, shorten, attach themselves to a solid surface, or harden their cuticle. The larvae easily slip free of their cuticle when dissected, indicating that apolysis of the larval cuticle has been completed.