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General Information
Symbol
Dmel\RhoGEF25.1
Species
D. melanogaster
Name
FlyBase ID
FBal0085928
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
point mutation
Nucleotide change:

G17041691C

Amino acid change:

G1788R | RhoGEF2-PD; G1434R | RhoGEF2-PE; G1788R | RhoGEF2-PF; G1786R | RhoGEF2-PG; G1685R | RhoGEF2-PH

Reported amino acid change:

G1788R

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Amino acid replacement: G1788R.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

RhoGEF25.1/RhoGEF24.1 animals show 50% embryonic viability, 13% first larval instar viability and 0% adult viability. Muscle and neuronal tissues show no significant defects in gross morphology in late-stage RhoGEF25.1/RhoGEF24.1 embryos.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressor of
Statement
Reference

RhoGEF25.1 is a suppressor of visible phenotype of Rho1GMR.PH

Phenotype Manifest In
Suppressor of
Statement
Reference

RhoGEF25.1 is a suppressor of eye phenotype of Rho1GMR.PH

Additional Comments
Genetic Interactions
Statement
Reference

Dominantly suppresses the Rho1GMR.PH rough eye phenotype.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
Comments
Comments

Isolated as a dominant suppressor of the Rho1GMR.PH rough eye phenotype.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (3)