antimorphic allele - genetic evidence
G1788R | RhoGEF2-PD; G1434R | RhoGEF2-PE; G1788R | RhoGEF2-PF; G1786R | RhoGEF2-PG; G1685R | RhoGEF2-PH
Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.
Amino acid replacement: G1788R.
lethal - all die during embryonic stage (with RhoGEF24.1)
lethal - all die during first instar larval stage (with RhoGEF24.1)
RhoGEF25.1/RhoGEF24.1 animals show 50% embryonic viability, 13% first larval instar viability and 0% adult viability. Muscle and neuronal tissues show no significant defects in gross morphology in late-stage RhoGEF25.1/RhoGEF24.1 embryos.
RhoGEF25.1 is a suppressor of visible phenotype of Rho1GMR.PH
RhoGEF25.1 is a suppressor of eye phenotype of Rho1GMR.PH
Dominantly suppresses the Rho1GMR.PH rough eye phenotype.
Isolated as a dominant suppressor of the Rho1GMR.PH rough eye phenotype.