FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Sin3Ae64
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General Information
Symbol
Dmel\Sin3Ae64
Species
D. melanogaster
Name
FlyBase ID
FBal0086752
Feature type
allele
Associated gene
Dmel\Sin3A
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Neufeld et al., 1998)
X ray
(Neufeld et al., 1998)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous Sin3Ae64 embryos display strong patterning defects, including germband retraction failure. Unfused myoblasts are observed, and a segmentally repeated muscle pattern cannot be distinguished.

      (Dobi et al., 2014)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      Sin3Ae64 is an enhancer of phenotype of sinaGMR.PN

      (Neufeld et al., 1998)

      Sin3Ae64 is an enhancer of phenotype of sina4

      (Neufeld et al., 1998)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Complements

      Sin3A26

      (Razzaq et al., 2001)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      Selected as: Dominant modifier of the sinaGMR.PN eye phenotype.

      (Neufeld et al., 1998)
      Comments
      Comments

      "ethyl methanesulfonate" was stated as tentative. "X ray" was stated as tentative.

      (Neufeld et al., 1998)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      ES2-3e64
      (Neufeld et al., 1998)
      Sin3Ae64
      (Dobi et al., 2014)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)