FlyBase Allele Report: Dmel\Psa[06226]

General Information

Symbol

Dmel\Psa⁰⁶²²⁶

Species

D. melanogaster

Name

FlyBase ID

FBal0086963

Feature type

allele

Associated gene

Dmel\Psa

Associated Insertion(s)

P{PZ}Psa⁰⁶²²⁶

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(BDGP Project Members, 1994-1999)

Progenitor genotype

Associated Insertion(s)

P{PZ}Psa⁰⁶²²⁶

Cytology

Description

Insertion in the 5' UTR.

(Karsten et al., 2006)

Allele components

Component

Use(s)

Inserted element

P{PZ}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

3L:1,517,292..1,517,292 [+]

(Karsten et al., 2006, BDGP Project Members, 1994-1999)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

exacerbates tauopathy

modeled by Hsap\MAPT^GMR.Ex.PJ

(Karsten et al., 2006)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(BDGP Project Members, 1994-1999)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

Psa⁰⁶²²⁶ is an enhancer of visible phenotype of Hsap\MAPT^GMR.Ex.PJ

(Karsten et al., 2006)

NOT Enhancer of

Statement

Reference

Psa⁰⁶²²⁶/l(3)06226[+] is a non-enhancer of visible phenotype of Hsap\HTT^{1-78.Q120.UAS}, Scer\GAL4^GMR.PF

(Karsten et al., 2006)

Psa⁰⁶²²⁶/l(3)06226[+] is a non-enhancer of visible phenotype of Scer\GAL4^GMR.PF, rpr^GMR.PH

(Karsten et al., 2006)

NOT Suppressor of

Statement

Reference

Psa⁰⁶²²⁶/l(3)06226[+] is a non-suppressor of visible phenotype of Hsap\HTT^{1-78.Q120.UAS}, Scer\GAL4^GMR.PF

(Karsten et al., 2006)

Psa⁰⁶²²⁶/l(3)06226[+] is a non-suppressor of visible phenotype of Scer\GAL4^GMR.PF, rpr^GMR.PH

(Karsten et al., 2006)

Phenotype Manifest In

Enhancer of

Statement

Reference

Psa⁰⁶²²⁶ is an enhancer of eye phenotype of Hsap\MAPT^GMR.Ex.PJ

(Karsten et al., 2006)

NOT Enhancer of

Statement

Reference

Psa⁰⁶²²⁶/l(3)06226[+] is a non-enhancer of eye phenotype of Hsap\HTT^{1-78.Q120.UAS}, Scer\GAL4^GMR.PF

(Karsten et al., 2006)

Psa⁰⁶²²⁶/l(3)06226[+] is a non-enhancer of eye phenotype of Scer\GAL4^GMR.PF, rpr^GMR.PH

(Karsten et al., 2006)

NOT Suppressor of

Statement

Reference

Psa⁰⁶²²⁶/l(3)06226[+] is a non-suppressor of eye phenotype of Hsap\HTT^{1-78.Q120.UAS}, Scer\GAL4^GMR.PF

(Karsten et al., 2006)

Psa⁰⁶²²⁶/l(3)06226[+] is a non-suppressor of eye phenotype of Scer\GAL4^GMR.PF, rpr^GMR.PH

(Karsten et al., 2006)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

The rough eye phenotype caused by Hsap\MAPT^GMR.Ex.PJ is enhanced by Psa⁰⁶²²⁶/+.

(Karsten et al., 2006)

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

10158

P{PZ}Psa⁰⁶²²⁶ ry⁵⁰⁶/TM3, ry^RK Sb¹ Ser¹

Notes on Origin

Discoverer

Comments

This allele was listed in the BDGP database as a lethal or sterile line during the period 1994-1999, but was discarded from the gene disruption project prior to the summary publication (FBrf0111489). Reasons for excluding lines from the collection described in FBrf0111489 include presence of more than one P insertion on the mutant chromosome, separation of lethality (or sterility) from the location of the insertion, and loss of lethality (or sterility) from the stock. Further information is available from http://www.fruitfly.org/bfd/ and from Dr. Spradling (spradling@mail1.ciwemb.edu).

Complements: l(3)j6B4^j6B4. Complements: l(3)rK315^rK315.

(BDGP Project Members, 1994-1999)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Psa⁰⁶²²⁶

l(3)06226

(Karsten et al., 2006)

l(3)06226⁰⁶²²⁶

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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