Flies expressing rprGMR.PH have a reduced eye, due to increased cell death.
rprGMR.PH flies have a smaller eye than normal.
rprGMR.PH eyes are small and rough.
Flies expressing rprGMR.PH have smaller eyes than normal.
Flies expressing rprGMR.PH show an eye ablation phenotype.
Flies that express rprGMR.PH have small eyes.
Mutant animals have small rough eyes.
Expression of rprGMR.PH leads to an almost complete elimination of the eye.
Expression of rprGMR.PH results in a small eye phenotype.
Cell death-dependent small eye phenotype.
Flies have small eyes.
rprGMR.PH has visible phenotype, enhanceable by CG8830[+]/DUBAIKG07439
rprGMR.PH has visible phenotype, enhanceable by Df(3L)mir-banΔ1
rprGMR.PH has increased cell death phenotype, enhanceable by BruceE12
rprGMR.PH has increased cell death phenotype, enhanceable by BruceE16
rprGMR.PH has visible phenotype, enhanceable by Psn+14.UAS/Scer\GAL4GMR.PF
rprGMR.PH has visible phenotype, enhanceable by Psn-14.UAS/Scer\GAL4GMR.PF
rprGMR.PH has visible phenotype, enhanceable by Scer\GAL4GMR.PF/PsnM146V.UAS
rprGMR.PH has visible phenotype, enhanceable by PsnN141I.UAS/Scer\GAL4GMR.PF
Scer\GAL4GMR.PF, rprGMR.PH has visible phenotype, non-enhanceable by Psa06226/l(3)06226[+]
Scer\GAL4GMR.PF, rprGMR.PH has visible phenotype, non-enhanceable by Psahs.PK
rprGMR.PH has increased cell death phenotype, non-enhanceable by BruceBIR.GMR
rprGMR.PH has visible phenotype, suppressible by Scer\GAL4GMR.PF/CorpEY03495
rprGMR.PH has increased cell death phenotype, suppressible by Scer\GAL4GMR.PF/CorpEY03495
rprGMR.PH has visible phenotype, suppressible by AckUAS.cSb/Scer\GAL4GMR.PU
rprGMR.PH has visible phenotype, suppressible by AckK156A.UAS/Scer\GAL4GMR.PU
rprGMR.PH has visible phenotype, suppressible by mir-banEP3622/Scer\GAL4GMR.PF
rprGMR.PH has decreased cell death phenotype, suppressible by qkr58E-3minus
rprGMR.PH has decreased cell death phenotype, suppressible by DreddB118
rprGMR.PH has increased cell death phenotype, suppressible by BruceGMREP-86a-2
rprGMR.PH has increased cell death phenotype, suppressible by BruceGMREP-86a-3
rprGMR.PH has increased cell death phenotype, suppressible by BruceGMREP-86a-4
rprGMR.PH has increased cell death phenotype, suppressible by BruceGMREP-86a-5
rprGMR.PH has increased cell death phenotype, suppressible by BruceGMREP-86a-1/BruceRNAi.GMR
rprGMR.PH has increased cell death phenotype, suppressible by BruceGMREP-86a-1
rprGMR.PH has visible phenotype, suppressible by DroncC318S.GMR
rprGMR.PH has abnormal cell death phenotype, suppressible by Diap2GMR.PH
rprGMR.PH has abnormal cell death phenotype, suppressible by Diap1GMR.PH
Scer\GAL4GMR.PF, rprGMR.PH has visible phenotype, non-suppressible by Psa06226/l(3)06226[+]
Scer\GAL4GMR.PF, rprGMR.PH has visible phenotype, non-suppressible by Psahs.PK
rprGMR.PH has visible phenotype, non-suppressible by spenDN.UAS/Scer\GAL4GMR.PF
rprGMR.PH has increased cell death phenotype, non-suppressible by BruceBIR.GMR
rprGMR.PH has increased cell death phenotype, non-suppressible by P{EP}stich1EP359
rprGMR.PH has increased cell death phenotype, non-suppressible by jumu06142a
rprGMR.PH has increased cell death phenotype, non-suppressible by jumu06439
rprGMR.PH has increased cell death phenotype, non-suppressible by jumuEP739
rprGMR.PH has increased cell death phenotype, non-suppressible by l(3)j8B6j8B6
Ack[+]/Ack86, rprGMR.PH has lethal | pharate adult stage phenotype
AckGD8506, Scer\GAL4GMR.PU, rprGMR.PH has visible phenotype
AckGD8506, Scer\GAL4GMR.PU, rprGMR.PH has lethal | pharate adult stage phenotype
Rab11N124I.UAS, Scer\GAL4GMR.PF, rprGMR.PH has visible phenotype
rprGMR.PH has eye phenotype, enhanceable by CG8830[+]/DUBAIKG07439
rprGMR.PH has eye phenotype, enhanceable by Df(3L)mir-banΔ1
rprGMR.PH has eye phenotype, enhanceable by mir-14k10213
rprGMR.PH has eye phenotype, enhanceable by Psn+14.UAS/Scer\GAL4GMR.PF
rprGMR.PH has eye phenotype, enhanceable by Psn-14.UAS/Scer\GAL4GMR.PF
rprGMR.PH has eye phenotype, enhanceable by Scer\GAL4GMR.PF/PsnM146V.UAS
rprGMR.PH has eye phenotype, enhanceable by PsnN141I.UAS/Scer\GAL4GMR.PF
Scer\GAL4GMR.PF, rprGMR.PH has eye phenotype, non-enhanceable by Psa06226/l(3)06226[+]
Scer\GAL4GMR.PF, rprGMR.PH has eye phenotype, non-enhanceable by Psahs.PK
rprGMR.PH has eye phenotype, non-enhanceable by BruceBIR.GMR
rprGMR.PH has phenotype, non-enhanceable by PsnD-ALG3.UAS/Scer\GAL4GMR.PF
rprGMR.PH has phenotype, non-enhanceable by Scer\GAL4GMR.PF/Psn+14.loop.UAS
rprGMR.PH has phenotype, non-enhanceable by Psn-14.loop.UAS/Scer\GAL4GMR.PF
rprGMR.PH has phenotype, non-enhanceable by Scer\GAL4GMR.PF/PsnL235P.UAS
rprGMR.PH has phenotype, non-enhanceable by PsnE280A.UAS/Scer\GAL4GMR.PF
rprGMR.PH has eye phenotype, suppressible by Scer\GAL4GMR.PF/CorpEY03495
rprGMR.PH has eye phenotype, suppressible by AckUAS.cSb/Scer\GAL4GMR.PU
rprGMR.PH has eye phenotype, suppressible by AckK156A.UAS/Scer\GAL4GMR.PU
rprGMR.PH has eye phenotype, suppressible by Df(2L)TW161
rprGMR.PH has eye phenotype, suppressible by mir-banEP3622/Scer\GAL4GMR.PF
rprGMR.PH has eye phenotype, suppressible by qkr58E-3minus
rprGMR.PH has eye phenotype, suppressible by BuffyΔN.UAS.Tag:FLAG/Scer\GAL4GMR.PF
rprGMR.PH has eye phenotype, suppressible by BuffyUAS.cQa/Scer\GAL4GMR.PF
rprGMR.PH has eye phenotype, suppressible by mir-14+t3.4
rprGMR.PH has eye phenotype, suppressible by mir-14GMR.PX
rprGMR.PH has eye phenotype, suppressible by Diap1GMR.PH
rprGMR.PH has eye phenotype, suppressible by BruceGMREP-86a-1
rprGMR.PH has eye phenotype, suppressible by BruceGMREP-86a-2
rprGMR.PH has eye phenotype, suppressible by BruceGMREP-86a-3
rprGMR.PH has eye phenotype, suppressible by BruceGMREP-86a-4
rprGMR.PH has eye phenotype, suppressible by BruceGMREP-86a-5
rprGMR.PH has eye phenotype, suppressible by BruceGMREP-86a-1/BruceRNAi.GMR
rprGMR.PH has phenotype, suppressible by lilliXS407
rprGMR.PH has phenotype, suppressible by lilliXS575
rprGMR.PH has eye phenotype, suppressible by DroncC318S.GMR
Scer\GAL4GMR.PF, rprGMR.PH has eye phenotype, non-suppressible by Psa06226/l(3)06226[+]
Scer\GAL4GMR.PF, rprGMR.PH has eye phenotype, non-suppressible by Psahs.PK
rprGMR.PH has eye phenotype, non-suppressible by spenDN.UAS/Scer\GAL4GMR.PF
rprGMR.PH has eye phenotype, non-suppressible by BruceBIR.GMR
rprGMR.PH has eye phenotype, non-suppressible by P{EP}stich1EP359
rprGMR.PH has eye phenotype, non-suppressible by jumu06142a
rprGMR.PH has eye phenotype, non-suppressible by l(3)j8B6j8B6
rprGMR.PH has phenotype, non-suppressible by Scer\GAL4GMR.PF/PsnL235P.UAS
rprGMR.PH has phenotype, non-suppressible by PsnE280A.UAS/Scer\GAL4GMR.PF
rprGMR.PH has phenotype, non-suppressible by PsnD-ALG3.UAS/Scer\GAL4GMR.PF
rprGMR.PH has phenotype, non-suppressible by Scer\GAL4GMR.PF/Psn+14.loop.UAS
rprGMR.PH has phenotype, non-suppressible by Psn-14.loop.UAS/Scer\GAL4GMR.PF
rprGMR.PH is an enhancer of eye phenotype of EBV\BZLF1GMR.PA
rprGMR.PH is an enhancer of eye phenotype of Scer\GAL4hs.2sev, mblC.UAS
rprGMR.PH is a suppressor of eye phenotype of EBV\BRLF1GMR.PA
AckGD8506, Scer\GAL4GMR.PU, rprGMR.PH has eye phenotype
Rab11N124I.UAS, Scer\GAL4GMR.PF, rprGMR.PH has eye phenotype
Expression of CorpEY03495 under the control of Scer\GAL4GMR.PF suppresses the increased cell death and reduced eye phenotypes caused by expression of rprGMR.PH.
Expression of either AckScer\UAS.cSb or AckK156A.Scer\UAS under the control of Scer\GAL4GMR.PU suppresses the reduced eye size caused by rprGMR.PH.
Ack86/+ flies expressing rprGMR.PH fail to eclose. The pharate adults have eyes that are partially ablated. The ablated eye area is replaced by a hole in the head cuticle where eye tissue would normally reside and the optic lobe region of the brain is visible. The few female adult escapers (no male escapers are seen) have an eye that is slightly reduced in size compared to flies expressing rprGMR.PH in a wild-type background.
rprGMR.PH flies expressing AckGD8506 under the control of Scer\GAL4GMR.PU fail to eclose. The pharate adults show complete ablation of the eye. The ablated eye area is replaced by a hole in the head cuticle where eye tissue would normally reside and the optic lobe region of the brain is visible, and sometimes protrudes outside of the head.
Df(2L)TW161, l(2)38Ea36, l(2)38Ea46, and l(2)38Ea66 all suppress the eye ablation phenotype of flies that express rprGMR.PH. l(2)38Eb54 fails to suppress this phenotype.
Eye size is largely restored by co-expression of banEP3622 (driven by Scer\GAL4GMR.PF) with rprGMR.PH. The addition of Df(3L)banΔ1 to rprGMR.PH animals leads to a minor enhancement of the eye phenotype.
About 90% of rprGMR.PH, mir-14k10213 or rprGMR.PH, mir-14Δ1 animals die as pupae, those that survive show an enhanced small eye phenotype. The addition of mir-14+t3.4 to rprGMR.PH animals suppresses the small eye phenotype in a dose dependant manner.
When one of BruceGMREP-86a-1, BruceGMREP-86a-2, BruceGMREP-86a-3, BruceGMREP-86a-4 or BruceGMREP-86a-5 is added to rprGMR.PH, its cell death phenotype in the eye is suppressed. The addition of jumuEP739, jumu06142a, jumu06439, l(3)j8B6j8B6 or P{EP}stich1EP359 has no effect. When both BruceGMR.dsRNA and BruceGMREP-86a-1 are added to rprGMR.PH only a partial suppression of the cell death phenotype in the eye is seen. The addition of BruceE16 or BruceE12 enhances the cell death phenotype in the eye seen in rprGMR.PH animals alone. The addition of BruceBIR.GMR has no effect on the cell death phenotype in the eye seen in rprGMR.PH animals alone.
Co-expression of NcC318S.GMR suppresses the rprGMR.PH small eye phenotype.
The eye phenotype of flies expressing rprGMR.PH is enhanced by one copy of Psn+14.Scer\UAS or Psn-14.Scer\UAS expressed under the control of Scer\GAL4GMR.PF, weakly enhanced by one copy of PsnM146V.Scer\UAS or PsnN141I.Scer\UAS expressed under the control of Scer\GAL4GMR.PF and unaffected by one copy of PsnL235P.Scer\UAS, PsnE280A.Scer\UAS, PsnD-ALG3.Scer\UAS, Psn+14.loop.Scer\UAS or Psn-14.loop.Scer\UAS expressed under the control of Scer\GAL4GMR.PF.
rprGMR.PH is rescued by rprRNAi.UAS.cLa/Scer\GAL4GMR.PF