FB2026_02 , released June 18, 2026
Allele: Dmel\Psn-14.UAS
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General Information
Symbol
Dmel\Psn-14.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0101584
Feature type
allele
Associated gene
Dmel\Psn
Associated Insertion(s)
Carried in Construct
P{UAS-Psn.-14}
Key Links
Transgenic product class
wild_type
(Ye and Fortini, 1999)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Ye and Fortini, 1999)
Mutagen
in vitro construct
(Ye and Fortini, 1999)
Progenitor genotype
Carried in construct
P{UAS-Psn.-14}
Cytology
Description

UASt regulatory sequences drive expression of the wild-type short isoform of Psn.

(Ye and Fortini, 1999)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Psn
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of Psn-14.UAS under the control of Scer\GAL4Appl.G1a does not lead to axonal blockages in third instar larval segmental nerves compared to controls.

      (Banerjee et al., 2018)

      Flies carrying one copy of Psn-14.Scer\UAS expressed under the control of Scer\GAL4hs.2sev or Scer\GAL4GMR.PF are morphologically indistinguishable from wild type. Flies carrying two copies of Psn-14.Scer\UAS expressed under the control of Scer\GAL4GMR.PF have a rough eye phenotype. Flies carrying two copies of Psn+14.Scer\UAS expressed under the control of Scer\GAL4GMR.PF have a rough eye phenotype, which is strongly enhanced if the flies are also carrying one copy of Psn-14.Scer\UAS.

      (Ye and Fortini, 1999)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      Psn-14.UAS/Scer\GAL4GMR.PF is an enhancer of visible phenotype of rprGMR.PH

      (Ye and Fortini, 1999)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Enhances the eye phenotype of flies expressing rprGMR.PH when expressed under the control of Scer\GAL4GMR.PF.

      (Ye and Fortini, 1999)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Carried in a plasmid and transfected into S2 cells to study the effect of Psn protein on N protein processing.

      (Ye and Fortini, 1999)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Psn-14.Scer\UAS
      Psn-14.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (2)