FB2026_02 , released June 18, 2026
Allele: Dmel\CorpEY03495
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General Information
Symbol
Dmel\CorpEY03495
Species
D. melanogaster
Name
FlyBase ID
FBal0316248
Feature type
allele
Associated gene
Dmel\Corp
Associated Insertion(s)
P{EPgy2}CG1632EY03495
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    P{EPgy2}CG1632EY03495
    Cytology
    Description

    Insertion of a P{EPgy2} element upstream of Corp. Scer\GAL4-driven expression from the Scer\UAS sites present in the inserted element results in overexpression of Corp.

    (Chakraborty et al., 2015)
    Allele components
    Component
    Use(s)
    Inserted element
    P{EPgy2}
    Regulatory region(s)
    UASp
    Mutations Mapped to the Genome
    Curation Data
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Expression of CorpEY03495 under the control of Scer\GAL4ey.PH almost completely suppresses the eye ablation phenotype resulting from an irreparable DNA double-stranded break in the BARTL (Bar and Telomere Loss) assay.

        Expression of CorpEY03495 under the control of Scer\GAL4en.PU significantly reduces irradiation-induced apoptosis in the posterior compartment of the wing disc.

        Expression of CorpEY03495 under the control of Scer\GAL4nos.UTR.T:Hsim\VP16 inhibits the transmission of broken and then healed chromosomes through the male germline.

        (Chakraborty et al., 2015)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Suppressor of
        Statement
        Reference

        Scer\GAL4GMR.PF/CorpEY03495 is a suppressor of eye phenotype of p53GMR.Ex

        (Chakraborty et al., 2015)

        Scer\GAL4GMR.PF/CorpEY03495 is a suppressor of eye phenotype of hidGMR.PG

        (Chakraborty et al., 2015)

        Scer\GAL4GMR.PF/CorpEY03495 is a suppressor of eye phenotype of rprGMR.PH

        (Chakraborty et al., 2015)
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        Expression of CorpEY03495 under the control of Scer\GAL4GMR.PF suppresses the increased cell death and reduced eye phenotypes caused by expression of either p53GMR.Ex, hidGMR.PG or rprGMR.PH.

        (Chakraborty et al., 2015)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (1)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        CorpEY03495
        EP-corp+
        (Chakraborty et al., 2015)
        Name Synonyms
        Secondary FlyBase IDs
          References (1)