FlyBase Allele Report: Dmel\mod(mdg4)[unspecified]

General Information

Symbol

Dmel\mod(mdg4)^unspecified

Species

D. melanogaster

Name

FlyBase ID

FBal0088804

Feature type

allele

Associated gene

Dmel\mod(mdg4)

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Cytology

Description

FlyBase curator comment: this entry is used to capture phenotypic information when the particular allele (or allele combination) used by the author could not be determined but the context of the experiment suggests that the phenotype being described is some kind of loss of function.

(FlyBase Curators, 2025-)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

enhancer of variegation, with In(1)w^m4

(Sass and Henikoff, 1998)

enhancer of variegation, with In(1)w^m4h

(Cobbe et al., 2006)

enhancer of variegation, with In(2R)bw^VDe2

(Sass and Henikoff, 1998)

lethal - all die during embryonic stage | recessive

(Read et al., 2000)

some die during embryonic stage | recessive

(Read et al., 2000)

Phenotype Manifest In

embryo

(Read et al., 2000)

Detailed Description

Statement

Reference

No mutants survived to a stage that secretes embryonic cuticle. All have abnormalities during pre=cellular blastoderm stages that affect the normal distribution of nuclei.

(Read et al., 2000)

Enhances the position effect variegation at the w locus caused by In(1)w^m4 and enhances the position effect variegation at the bw locus caused by In(2R)bw^VDe2. Does not effect position effect variegation at the bw locus caused by Byron or the position effect variegation of w seen in the P{wA^R}41A insertion.

(Sass and Henikoff, 1998)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

mod(mdg4)^unspecified is a suppressor of visible phenotype of sc^mes21

(Golovnin et al., 1999)

mod(mdg4)^unspecified is a suppressor of visible phenotype of sc^mes26