FB2026_03 , released September 17, 2026
Allele: Dmel\Sec61βk03307
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General Information
Symbol
Dmel\Sec61βk03307
Species
D. melanogaster
Name
FlyBase ID
FBal0089113
Feature type
allele
Associated gene
Dmel\Sec61β
Associated Insertion(s)
P{lacW}Sec61βk03307
Carried in Construct
Also Known As
l(2)k03307
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(BDGP Project Members, 1994-1999)
Progenitor genotype
Associated Insertion(s)
P{lacW}Sec61βk03307
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Heterozygotes show eggshell phenotypes including forked and fused dorsal appendages.

      (Schnorr et al., 2001)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      Sec61beta[+]/Sec61βk03307 is a suppressor of visible | heat sensitive phenotype of peb1

      (Wilk et al., 2004)
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      Sec61beta[+]/Sec61βk03307 is an enhancer of dorsal appendage phenotype of Ras85Dix12a

      (Schnorr et al., 2001)
      Suppressor of
      Statement
      Reference

      Sec61beta[+]/Sec61βk03307 is a suppressor of eye | heat sensitive phenotype of peb1

      (Wilk et al., 2004)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Strong dominant enhancer of the Ras85Dix12a eggshell phenotype; 0-20% of dorsal appendages are wild type.

      (Schnorr et al., 2001)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer

      I. Kiss.

      (BDGP Project Members, 1994-1999)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (5)
      Reported As
      Symbol Synonym
      BL-10376
      (Rollmann et al., 2007)
      Sec61k03307
      (Wilk et al., 2004)
      Sec61βk03307
      l(2)07214k03307
      (BDGP Project Members, 1994-1999)
      l(2)k03307
      (Schnorr et al., 2001, Spradling et al., 1999)
      Name Synonyms
      Secondary FlyBase IDs
        References (6)