FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\cora1-383.hs.Tag:MYC
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General Information
Symbol
Dmel\cora1-383.hs.Tag:MYC
Species
D. melanogaster
Name
FlyBase ID
FBal0089385
Feature type
allele
Associated gene
Dmel\cora
Associated Insertion(s)
Carried in Construct
P{hs-cora.1-383.T:Myc}
Key Links
Transgenic product class
inframe_deletion
(Ward et al., 1998)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Ward et al., 1998)
Mutagen
in vitro construct
(Ward et al., 1998)
Progenitor genotype
Carried in construct
P{hs-cora.1-383.T:Myc}
Cytology
Description

Sequences encoding cora amino acids 1 to 383, tagged at the N-terminal end with Tag:MYC, are expressed under the control of a heat shock promoter.

(Ward et al., 1998)
Allele components
Component
Use(s)
Regulatory region(s)
Hsp70
Encoded product / tool
cora
Tagged with
Tag:MYC
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      cora1-383.hs.Tag:MYC rescues cora4

      (Ward et al., 2001)
      Partially rescues

      cora1-383.hs.Tag:MYC partially rescues cora5

      (Ward et al., 2001)
      Comments

      Fails to rescue cora5 animals to adulthood when expressed using heat shock. Rescues the embryonic defects of cora5 animals (dorsal open phenotype, cuticular thinning, necrosis of the salivary glands and tracheal inflation defect) when expressed using heat shock, with some animals hatching into larvae. The normal appearance of the septate junction is also restored in cora5 embryos expressing cora1-383.hs.T:Hsap\MYC and diffusion of rhodamine-dextran across the salivary gland epithelium is restricted (as in wild-type animals). Rescues the growth disadvantage of cora4 clones in the wing imaginal epithelium when expressed using daily heat shock.

      (Ward et al., 2001)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Carried in a plasmid and transfected into S2 cells to determine the subcellular localisation of the cora1-383.hs.T:Hsap\MYC protein.

      (Ward et al., 1998)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      cora1-383.hs.T:Hsap\MYC
      cora1-383.hs.T:Myc
      cora1-383.hs.Tag:MYC
      Name Synonyms
      Secondary FlyBase IDs
        References (2)