FB2026_02 , released June 18, 2026
Allele: Dmel\pleUAS.cTa
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General Information
Symbol
Dmel\pleUAS.cTa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of True
FlyBase ID
FBal0090174
Feature type
allele
Associated gene
Dmel\ple
Associated Insertion(s)
Carried in Construct
P{UAS-ple.T}
Also Known As
UAS-TH
Key Links
Transgenic product class
wild_type
(True et al., 1999)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(True et al., 1999)
Mutagen
in vitro construct
(True and Carroll, 1998)
Progenitor genotype
Carried in construct
P{UAS-ple.T}
Cytology
Description

A 2628bp EcoRI-HinDIII fragment containing the complete ple open reading frame is driven by UASt sequences.

(True et al., 1999)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
ple
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Flies expressing pleScer\UAS.cTa under the control of Scer\GAL4ple.PF show normal temperature-preference behaviour.

      (Bang et al., 2011)

      When pleScer\UAS.cTa is driven by Scer\GAL4ap-md544, Scer\GAL4ap-md544, Scer\GAL4Dll-md23 or Scer\GAL4en-e16E, no ectopic pigmentation is seen. If pleScer\UAS.cTa is driven by Scer\GAL4hs.2sev (with no heatshock) or Scer\GAL4how-24B, a gradual development of ectopic brown stripes in the intervein areas of the wings during adult life was seen.

      (True et al., 1999)

      Expression of pleScer\UAS.cTa under the control of Scer\GAL4unspecified results in lightening of the adult abdominal stripes and a low level of ectopic pigmentation in the intervein areas of the wing.

      (True and Carroll, 1998)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhanced by
      Suppressed by
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Flies co-expressing both DdcScer\UAS.cTa and pleScer\UAS.cTa under the control of Scer\GAL4ple.PF show abnormal temperature-preference behaviour; their avoidance index against high temperatures is only 39% of wild type.

      (Bang et al., 2011)

      Co-expressing pleScer\UAS.cTa and DdcScer\UAS.cTa under the control of Scer\GAL4hs.2sev leads to a more intense ectopic pigmentation phenotype than pleScer\UAS.cTa alone. The adult cuticle remains underpigmented.

      (True et al., 1999)

      Expression of pleScer\UAS.cTa together with DdcScer\UAS.cTa under the control of Scer\GAL4unspecified enhances the wing pigmentation phenotype and variably suppresses the abdominal pigmentation phenotype.

      (True and Carroll, 1998)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      pleScer\UAS.cTa
      pleUAS.cTa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of True
      (True and Carroll, 1998)
      Secondary FlyBase IDs
        References (10)