FlyBase Allele Report: Dmel\Ddc[UAS.cTa]

General Information

Symbol

Dmel\Ddc^UAS.cTa

Species

D. melanogaster

Name

Saccharomyces cerevisiae UAS construct a of True

FlyBase ID

FBal0090713

Feature type

allele

Associated gene

Dmel\Ddc

Associated Insertion(s)

Carried in Construct

P{UAS-Ddc.T}

Also Known As

UAS-DDC

Key Links

Transgenic product class

wild_type

(True et al., 1999)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(True et al., 1999)

Mutagen

in vitro construct

(True and Carroll, 1998)

Progenitor genotype

Carried in construct

P{UAS-Ddc.T}

Cytology

Description

A 1432bp EcoRI-KpnI fragment containing the complete hypoderm-specific Ddc open reading frame is driven by UASt sequences.

(True et al., 1999)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

Ddc

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

Flies expressing Ddc^Scer\UAS.cTa under the control of Scer\GAL4^ple.PF show normal temperature-preference behaviour.

(Bang et al., 2011)

Ddc^Scer\UAS.cTa when driven by Scer\GAL4^unspecified does not lead to ectopic pigmentation in adults.

(True et al., 1999)

Expression of Ddc^Scer\UAS.cTa under the control of Scer\GAL4^unspecified has no effect on adult pigmentation.

(True and Carroll, 1998)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

Ddc^UAS.cTa, Scer\GAL4^hs.2sev is an enhancer of abnormal body color phenotype of Scer\GAL4^hs.2sev, ple^UAS.cTa

(True et al., 1999)

Ddc^UAS.cTa, Scer\GAL4^unspecified is an enhancer of abnormal body color phenotype of Scer\GAL4^unspecified, ple^UAS.cTa

(True and Carroll, 1998)

NOT Enhancer of

Statement

Reference

Ddc^UAS.cTa, Scer\GAL4^pnr-MD237 is a non-enhancer of abnormal body color | adult stage phenotype of Rpn9^HMS05753, Scer\GAL4^pnr-MD237

(Zhang et al., 2021)

Suppressor of

Statement

Reference

Ddc^UAS.cTa, Scer\GAL4^unspecified is a suppressor of abnormal body color phenotype of Scer\GAL4^unspecified, ple^UAS.cTa

(True and Carroll, 1998)

NOT Suppressor of

Statement

Reference

Ddc^UAS.cTa, Scer\GAL4^pnr-MD237 is a non-suppressor of abnormal body color | adult stage phenotype of Rpn9^HMS05753, Scer\GAL4^pnr-MD237

(Zhang et al., 2021)

Ddc^UAS.cTa, Scer\GAL4^pnr-MD237 is a non-suppressor of abnormal body color | adult stage phenotype of Scer\GAL4^pnr-MD237, Vhl^KK111257

(Zhang et al., 2021)

Other

Statement

Reference

Ddc^UAS.cTa, Scer\GAL4^ple.PF has abnormal thermotaxis | adult stage phenotype

(Bang et al., 2011)

Phenotype Manifest In

Enhancer of

Statement

Reference

Ddc^UAS.cTa, Scer\GAL4^unspecified is an enhancer of wing cell phenotype of Scer\GAL4^unspecified, ple^UAS.cTa

(True and Carroll, 1998)

NOT Enhancer of

Statement

Reference

Ddc^UAS.cTa, Scer\GAL4^pnr-MD237 is a non-enhancer of adult external thorax phenotype of Rpn9^HMS05753, Scer\GAL4^pnr-MD237

(Zhang et al., 2021)

Suppressor of

Statement

Reference

Ddc^UAS.cTa, Scer\GAL4^unspecified is a suppressor of adult abdomen phenotype of Scer\GAL4^unspecified, ple^UAS.cTa

(True and Carroll, 1998)

NOT Suppressor of

Statement

Reference

Ddc^UAS.cTa, Scer\GAL4^pnr-MD237 is a non-suppressor of adult external thorax phenotype of Rpn9^HMS05753, Scer\GAL4^pnr-MD237

(Zhang et al., 2021)

Ddc^UAS.cTa, Scer\GAL4^pnr-MD237 is a non-suppressor of adult external thorax phenotype of Scer\GAL4^pnr-MD237, Vhl^KK111257

(Zhang et al., 2021)

Additional Comments

Genetic Interactions

Statement

Reference

Flies co-expressing both Ddc^Scer\UAS.cTa and ple^Scer\UAS.cTa under the control of Scer\GAL4^ple.PF show abnormal temperature-preference behaviour; their avoidance index against high temperatures is only 39% of wild type.

(Bang et al., 2011)

Co-expressing ple^Scer\UAS.cTa and Ddc^Scer\UAS.cTa under the control of Scer\GAL4^hs.2sev leads to a more intense ectopic pigmentation phenotype than ple^Scer\UAS.cTa alone. The adult cuticle remains underpigmented.

(True et al., 1999)

Ddc^Scer\UAS.cTa enhances the wing pigmentation phenotype and variably suppresses the abdominal pigmentation phenotype of flies expressing ple^Scer\UAS.cTa under the control of Scer\GAL4^unspecified.

(True and Carroll, 1998)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

37540

w^*; P{UAS-Ddc.T}16f2/TM3, Sb¹

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Ddc^Scer\UAS.cTa

Ddc^UAS.cTa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of True

(True and Carroll, 1998)

Secondary FlyBase IDs

References (8)

Report Sections

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