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General Information
Symbol
Dmel\panciD
Species
D. melanogaster
Name
FlyBase ID
FBal0090202
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Mutations Mapped to the Genome
     
    Type
    Location
    Additional Notes
    References
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
     
    Progenitor genotype
    Cytology
    Nature of the lesion
    Statement
    Reference

    In(4)ciD is an inversion in which the promoter regions and first exons of pan and ci have been swapped. panciD consists of a hybrid gene in which the ci promoter controls expression of a hybrid mRNA, predicted to start with the 5' region of ci up to 78 nucleotides before the ci start codon fused to a 135bp sequence of unknown origin which is in turn fused to the majority of the pan transcript (starting before the 10th exon, right before the HMG domain). This hybrid mRNA has a putative start codon directly downstream of the breakpoint in frame with the original pan open reading frame and is predicted to code for a truncated pan protein that lacks the N-terminal 280 amino acids.

    Insertion into the promoter region.

    Caused by aberration
    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease-implicated variant(s)
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference
    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Phenotype Manifest In
    Suppressor of
    Statement
    Reference

    panciD is a suppressor of eye photoreceptor cell phenotype of ApcQ8

    Additional Comments
    Genetic Interactions
    Statement
    Reference

    Some photoreceptors are rescued from death in ApcQ8 homozygotes carrying one copy of panciD.

    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Images (0)
    Mutant
    Wild-type
    Stocks (98)
    Notes on Origin
    Discoverer
    Comments
    Comments

    Second insertion of ciD.

    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (2)
    Reported As
    Symbol Synonym
    Name Synonyms
    Secondary FlyBase IDs
      References (8)