FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\panciD
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General Information
Symbol
Dmel\panciD
Species
D. melanogaster
Name
FlyBase ID
FBal0090202
Feature type
allele
Associated gene
Dmel\pan
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Caused by aberration
    In(4)ciD
    Cytology
    Description

    In(4)ciD is an inversion in which the promoter regions and first exons of pan and ci have been swapped. panciD consists of a hybrid gene in which the ci promoter controls expression of a hybrid mRNA, predicted to start with the 5' region of ci up to 78 nucleotides before the ci start codon fused to a 135bp sequence of unknown origin which is in turn fused to the majority of the pan transcript (starting before the 10th exon, right before the HMG domain). This hybrid mRNA has a putative start codon directly downstream of the breakpoint in frame with the original pan open reading frame and is predicted to code for a truncated pan protein that lacks the N-terminal 280 amino acids.

    (Schweizer and Basler, 1998)

    Insertion into the promoter region.

    (van de Wetering et al., 1997)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Suppressor of
        Statement
        Reference

        panciD is a suppressor of eye photoreceptor cell phenotype of ApcQ8

        (Ahmed et al., 1998)
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        Some photoreceptors are rescued from death in ApcQ8 homozygotes carrying one copy of panciD.

        (Ahmed et al., 1998)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Images (0)
        Mutant
        Wild-type
        Stocks (214)
        Notes on Origin
        Discoverer
        Comments
        Comments

        Second insertion of ciD.

        (van de Wetering et al., 1997)
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        ciD
        (Kronhamn and Rasmuson-Lestander, 1999)
        panciD
        Name Synonyms
        Secondary FlyBase IDs
          References (8)