FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Hr781
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General Information
Symbol
Dmel\Hr781
Species
D. melanogaster
Name
FlyBase ID
FBal0090634
Feature type
allele
Associated gene
Dmel\Hr78
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

amorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - genetic evidence

(Fisk and Thummel, 1998)
Mutagen
ethyl methanesulfonate
(Fisk and Thummel, 1998)
Progenitor genotype
Cytology
Description

Nucleotide substitution: G?A. Mutation at the splice acceptor site within intron 2.

(Fisk and Thummel, 1998)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
3L:21,495,869..21,495,869 [-]
Nucleotide change:

G21495869A

Reported nucleotide change:

G?A

Comment:

Reported as a G-to-A transition at the splice acceptor site.

(Fisk and Thummel, 1998)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Mutants die as third instar larvae. Mutant larvae exhibit asynchronous development at the second to third instar moult, reduced size during the third instar, tracheal defect and failure to pupariate.

      (Fisk and Thummel, 1998)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      Hr781 is rescued by Hr78hs.PF

      (Fisk and Thummel, 1998)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Selected as: F2 lethal that fails to complement Df(3L)10-2 and Df(3L)79-2.

      (Fisk and Thummel, 1998)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      DHR781
      (Fisk and Thummel, 1998)
      Hr781
      Name Synonyms
      Secondary FlyBase IDs
        References (1)