FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\αTub67CRE2.1
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General Information
Symbol
Dmel\αTub67CRE2.1
Species
D. melanogaster
Name
FlyBase ID
FBal0090814
Feature type
allele
Associated gene
Dmel\αTub67C
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Mathe et al., 1998)
Progenitor genotype
αTub67CTom-3a
(Mathe et al., 1998)
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Both meiosis I and II proceed normally in hemizygous females. Hemizygous females are sterile. Only a small sperm aster forms in many eggs derived from hemizygous females. There is no apparent female pronuclear specification or evidence of migration towards the male pronucleus. Triplo- or tetra-fusion of the polar bodies is common. The gonomeric division is not completed in eggs of hemizygous and heterozygous females.

      (Mathe et al., 1998)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Based on the extent of embryogenesis in eggs derived from hemizygous females, the following αTub67C alleles can be ranked from strongest to weakest as follows: αTub67CRE3.1 = αTub67CRE3.2 = αTub67CRE3.3 > αTub67CRE2.1 = αTub67CRX2.2 = αTub67CRX2.1 = αTub67CRE1.1 = αTub67CRX3.1 > αTub67CRX1.1 = αTub67CRP3.1 = αTub67CRP1.1. Transplantation experiments in which αTub67CRE2.1/αTub67CRE3.1 germ line cells are transplanted into ovoD1/+ females, and normal germ line cells are transplanted into αTub67CRE2.1/αTub67CRE3.1 females indicate that αTub67C functions only in the female germ line.

      (Mathe et al., 1998)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      αTub67CRE2.1
      Name Synonyms
      Secondary FlyBase IDs
        References (1)