FB2026_03 , released September 17, 2026
Allele: Dmel\vas15
Open Close
General Information
Symbol
Dmel\vas15
Species
D. melanogaster
Name
FlyBase ID
FBal0091103
Feature type
allele
Associated gene
Dmel\vas
Associated Insertion(s)
P{lacW}vas15
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Tomancak et al., 1998)
Progenitor genotype
Associated Insertion(s)
P{lacW}vas15
Cytology
Description

Insertion in the 5' non-coding first exon of vas.

(Tomancak et al., 1998)

Insertion in the first (non-coding) exon that is common to both vas and solo.

(FlyBase, 1996-)
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous females lay variably ventralised eggs, the phenotype ranging from complete loss of dorsal appendage material through to wild-type dorsal appendages. Occasionally, immature eggs in the ovary with a micropyle at both the anterior and posterior pole are seen. These eggs are not laid. Homozygous stage 10 egg chambers often have a constriction close to the posterior pole of the oocyte. Homozygous ovaries are significantly smaller than wild-type and have various structural defects. The oocyte is mispositioned in 5% of egg chambers. vas15/vas3 or vas15/Df(2L)A267 females produce eggs with more severe anterior-posterior and dorsal-ventral polarity phenotypes than homozygous vas15 females. 100% of eggs laid by vas1/vas15 females appear wild-type.

      (Tomancak et al., 1998)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      vas15
      Name Synonyms
      Secondary FlyBase IDs
        References (2)