FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\sktlk12405
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General Information
Symbol
Dmel\sktlk12405
Species
D. melanogaster
Name
FlyBase ID
FBal0094331
Feature type
allele
Associated gene
Dmel\sktl
Associated Insertion(s)
P{lacW}insck12405
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Kania et al., 1995)
Progenitor genotype
Associated Insertion(s)
P{lacW}insck12405
Cytology
Description

Insertion of a P{lacW} element.

(Kania et al., 1995)
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous embryos exhibit elongation of lateral chordotonal (Lch) neuron cell bodies and dendrites and subtle pathfinding defects.

      (Kania et al., 1995)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      sktl05475

      (BDGP Project Members, 1994-1999)
      Comments

      Since sktl is nested within an intron of insc, and the locus corresponds to that previously known as 'fam', all alleles previously ascribed to 'fam' are considered to be alleles of both sktl and insc until shown to be otherwise.

      (FlyBase, 1996-)
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer

      I. Kiss.

      Comments
      Comments

      P{lacW} insertion can be excised and revert the lethal phenotype to wild type.

      (Kania et al., 1995)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      124/5
      (Kania et al., 1995)
      famk12405
      sktlk12405
      Name Synonyms
      Secondary FlyBase IDs
      • FBal0043062
      References (4)