FB2026_02 , released June 18, 2026
Allele: Dmel\ind16.2
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General Information
Symbol
Dmel\ind16.2
Species
D. melanogaster
Name
FlyBase ID
FBal0094519
Feature type
allele
Associated gene
Dmel\ind
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Weiss et al., 1998)
Progenitor genotype
P{PZ}l(3)rO220rO220
(Weiss et al., 1998)
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Only 10% of the intermediate column neuroblasts develop in homozygous embryos, although adjacent ventral and dorsal column neuroblasts form normally. RP2 neurons are missing in these embryos.

      (Weiss et al., 1998)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      ind[+]/ind16.2 is an enhancer of abnormal neuroanatomy phenotype of D87

      (Zhao and Skeath, 2002)
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      ind[+]/ind16.2 is an enhancer of larval RP2 motor neuron phenotype of D87

      (Zhao and Skeath, 2002)
      Other
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      ind16.2/+ ; SoxNC2139 embryos show an increased loss of neuroblasts compared to SoxNC2139 single mutants; NB5-3 is lost in 46% of hemisegments, and the RP2 neurons shows 99% loss.

      (Buescher et al., 2002)

      D87 ind16.2/D87 + embryos lack 42.4% of RP2 neurons.

      (Zhao and Skeath, 2002)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      References (11)