FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Allele: Dmel\fraC1-62
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General Information
Symbol
Dmel\fraC1-62
Species
D. melanogaster
Name
FlyBase ID
FBal0095415
Feature type
allele
Associated gene
Dmel\fra
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

hypomorphic allele - genetic evidence

Mutagen
    Nature of the Allele
    Allele class

    hypomorphic allele - genetic evidence

    (Hummel et al., 1999)
    Mutagen
    Progenitor genotype
    Cytology
    Description
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Homozygotes show a mild reduction in the number of commissural fibers in both anterior and posterior commissures.

        (Hummel et al., 1999)

        2-4 neuromeres lack one commissure in homozygous embryos.

        (Hummel et al., 1999)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Enhanced by
        Statement
        Reference

        fraC1-62 has larval ventral nerve cord commissure phenotype, enhanceable by IqsecU112

        (Hummel et al., 1999)
        Enhancer of
        Statement
        Reference

        fraC1-62 is an enhancer of larval ventral nerve cord commissure phenotype of IqsecU112

        (Hummel et al., 1999)
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        sizU112 fraC1-62 double mutant embryos lack most commissural axons.

        (Hummel et al., 1999)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        fraC1-62
        Name Synonyms
        Secondary FlyBase IDs
          References (2)